ALPL_ARATH
ID ALPL_ARATH Reviewed; 406 AA.
AC Q9M2U3;
DT 30-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Protein ALP1-like {ECO:0000305};
DE EC=3.1.-.-;
GN OrderedLocusNames=At3g55350 {ECO:0000312|Araport:AT3G55350};
GN ORFNames=T22E16.10 {ECO:0000312|EMBL:CAB75893.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transposase-derived protein that may have nuclease activity.
CC {ECO:0000305}.
CC -!- COFACTOR:
CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC Evidence={ECO:0000250|UniProtKB:Q96MB7};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q94K49,
CC ECO:0000255|PROSITE-ProRule:PRU00768}.
CC -!- SIMILARITY: Belongs to the HARBI1 family. {ECO:0000305}.
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DR EMBL; AL132975; CAB75893.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE79371.1; -; Genomic_DNA.
DR EMBL; AK117365; BAC42035.1; -; mRNA.
DR EMBL; BT009674; AAP80175.1; -; mRNA.
DR EMBL; AY087712; AAM65249.1; -; mRNA.
DR PIR; T47674; T47674.
DR RefSeq; NP_191095.1; NM_115393.3.
DR AlphaFoldDB; Q9M2U3; -.
DR SMR; Q9M2U3; -.
DR STRING; 3702.AT3G55350.1; -.
DR PaxDb; Q9M2U3; -.
DR PRIDE; Q9M2U3; -.
DR ProteomicsDB; 245026; -.
DR DNASU; 824701; -.
DR EnsemblPlants; AT3G55350.1; AT3G55350.1; AT3G55350.
DR GeneID; 824701; -.
DR Gramene; AT3G55350.1; AT3G55350.1; AT3G55350.
DR KEGG; ath:AT3G55350; -.
DR Araport; AT3G55350; -.
DR TAIR; locus:2099901; AT3G55350.
DR eggNOG; KOG4585; Eukaryota.
DR HOGENOM; CLU_018552_3_4_1; -.
DR InParanoid; Q9M2U3; -.
DR OMA; LHHLCWP; -.
DR OrthoDB; 822378at2759; -.
DR PhylomeDB; Q9M2U3; -.
DR PRO; PR:Q9M2U3; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M2U3; baseline and differential.
DR GO; GO:0000118; C:histone deacetylase complex; IDA:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR InterPro; IPR045249; HARBI1-like.
DR InterPro; IPR027806; HARBI1_dom.
DR PANTHER; PTHR22930; PTHR22930; 1.
DR Pfam; PF13359; DDE_Tnp_4; 1.
PE 2: Evidence at transcript level;
KW Hydrolase; Metal-binding; Nuclease; Nucleus; Reference proteome.
FT CHAIN 1..406
FT /note="Protein ALP1-like"
FT /id="PRO_0000438515"
FT DOMAIN 187..353
FT /note="DDE Tnp4"
FT /evidence="ECO:0000255"
FT MOTIF 8..15
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT BINDING 188
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /evidence="ECO:0000255"
FT BINDING 240
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /evidence="ECO:0000255"
FT BINDING 279
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /evidence="ECO:0000255"
SQ SEQUENCE 406 AA; 45467 MW; 0569E1B27BCE1452 CRC64;
MGPIKTIKKK KRAEKKVDRN VLLAATAAAT SASAAAALNN NDDDDDSSSQ SLDWWDGFSR
RIYGGSTDPK TFESVFKISR KTFDYICSLV KADFTAKPAN FSDSNGNPLS LNDRVAVALR
RLGSGESLSV IGETFGMNQS TVSQITWRFV ESMEERAIHH LSWPSKLDEI KSKFEKISGL
PNCCGAIDIT HIVMNLPAVE PSNKVWLDGE KNFSMTLQAV VDPDMRFLDV IAGWPGSLND
DVVLKNSGFY KLVEKGKRLN GEKLPLSERT ELREYIVGDS GFPLLPWLLT PYQGKPTSLP
QTEFNKRHSE ATKAAQMALS KLKDRWRIIN GVMWMPDRNR LPRIIFVCCL LHNIIIDMED
QTLDDQPLSQ QHDMNYRQRS CKLADEASSV LRDELSDQLC GKNSSA
