ID   GEP3_CANAW              Reviewed;         629 AA.
AC   C4YPB0;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Genetic interactor of prohibitins 3, mitochondrial;
DE   AltName: Full=Found in mitochondrial proteome protein 38;
DE   Flags: Precursor;
GN   Name=GEP3; Synonyms=FMP48; ORFNames=CAWG_03061;
OS   Candida albicans (strain WO-1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: May be involved in the mitochondrial lipid metabolism.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
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DR   EMBL; CM000310; EEQ44769.1; -; Genomic_DNA.
DR   AlphaFoldDB; C4YPB0; -.
DR   STRING; 5476.C4YPB0; -.
DR   EnsemblFungi; EEQ44769; EEQ44769; CAWG_03061.
DR   VEuPathDB; FungiDB:CAWG_03061; -.
DR   HOGENOM; CLU_025792_0_0_1; -.
DR   OMA; QIVKYIP; -.
DR   Proteomes; UP000001429; Chromosome 3.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Transit peptide.
FT   TRANSIT         1..19
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..629
FT                   /note="Genetic interactor of prohibitins 3, mitochondrial"
FT                   /id="PRO_0000409629"
FT   DOMAIN          171..374
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   REGION          104..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..122
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   629 AA;  72517 MW;  FF8644D0DB5D1E2A CRC64;
     MFSRSILLRS VRKSLGRYYS SQAHPQTYIY NLLSDTKCRS CGIQLQDKFP DKPGYYRLPG
     QNDSNTDNKA KTSELNKKYE KILQNLDISD RNLLINNFSA PKQDDEKVTS VPSLQQITPV
     EADTRDTTKD QQTHSGHSLS CKRCNDVIYN SKTRSIYDPN RDNLNKSEFP IPKLQQVLST
     IPVDAPLVYV FSANDFPMGI NKDIFQYRPP QQIYFVMTKS DILIPKTNVA FYNNFKKFLQ
     NYMFKKFNVP RENVFIASGK DRWKMTDLYH FIPNYSYIIG DTNCGKSTLV KSLLINHHVK
     HWKYEARQQR PDEKQSSSAS LKNKDFKKLD RLIDSFSSKN GPGTSHIPGF TRDVLPVDID
     GIKELFDVPG FTTNENLQDI FDKLNHKQIA RITKGANTSK YGSLKSKFDT VKNGQVLSLN
     GVGYLQFPGQ DSMYQIRNVT KFALHKFKNL EKVDSILQRN EIPKSMSSHF IVNRQQQQQQ
     RNELRGYYKR YIIPPFYGTI DLVIKDIGYI NIKPTGKKLT NELMVLYLHP SLEAIIRQPI
     LNYIDPPTPK KSPDGTNRKT ITSDISKTPF YSRLIPSTVL SDPSSLVLSP PSSDYNQLNQ
     YLQIDESSES AYNDLLELDE TNKYDYWIE