ID   GEP3_CANGA              Reviewed;         526 AA.
AC   Q8TFK7; F2Z674; Q6FLJ7;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Genetic interactor of prohibitins 3, mitochondrial;
DE   AltName: Full=Found in mitochondrial proteome protein 38;
DE   Flags: Precursor;
GN   Name=GEP3; Synonyms=FMP48; OrderedLocusNames=CAGL0L02893g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=12125055; DOI=10.1002/yea.890;
RA   Walsh D.W., Wolfe K.H., Butler G.;
RT   "Genomic differences between Candida glabrata and Saccharomyces cerevisiae
RT   around the MRPL28 and GCN3 loci.";
RL   Yeast 19:991-994(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in the mitochondrial lipid metabolism.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
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DR   EMBL; AY083607; AAM08103.1; -; Genomic_DNA.
DR   EMBL; CR380958; CAG61867.1; -; Genomic_DNA.
DR   RefSeq; XP_448897.1; XM_448897.1.
DR   AlphaFoldDB; Q8TFK7; -.
DR   STRING; 5478.XP_448897.1; -.
DR   EnsemblFungi; CAG61867; CAG61867; CAGL0L02893g.
DR   GeneID; 2890836; -.
DR   KEGG; cgr:CAGL0L02893g; -.
DR   CGD; CAL0135692; CAGL0L02893g.
DR   VEuPathDB; FungiDB:CAGL0L02893g; -.
DR   eggNOG; ENOG502S0UP; Eukaryota.
DR   HOGENOM; CLU_025792_1_0_1; -.
DR   InParanoid; Q8TFK7; -.
DR   OMA; QIVKYIP; -.
DR   Proteomes; UP000002428; Chromosome L.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:EnsemblFungi.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; IEA:EnsemblFungi.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..14
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           15..526
FT                   /note="Genetic interactor of prohibitins 3, mitochondrial"
FT                   /id="PRO_0000409631"
FT   DOMAIN          105..293
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
SQ   SEQUENCE   526 AA;  61413 MW;  F6DCAF8762CEB6EE CRC64;
     MRFRRYFSST FKRLIDCNSC GVKLQNKQPG ALGYYTKKDD NLVKKITLED VKYLIFGQDI
     QRIKEMTVDT ENYDIKLEKP LICKRCSEAL HNNKYNATEF KDIPFEEVEK QIPLHSNVVH
     TAPILEFPFH INSQLLKNRT FNTTMVFTKA DRVFKNKKQV QKQIPIFLDA FFETYLNSKA
     TRNIVTSTLN RWNLDTLFSF LHGTNYFVGE PNSGKSTLIN ALLRRLFGVK IRGNDVKNFE
     LDKQAEEELA VSKKFFLEKQ LAGVSHIPNL TRTLQAYKIK QKIIYDLPGY SNYNSYRIDE
     FIDPKWLQRF RKTSIFSEKR VKKKRYDSIV GNENGKCLTL GGIFYLVPPP TTINQIVCYI
     PGELRQFHNT DRGIEVLGKS GSKEHPLNKY CGIKPGIGKE KYIRHIIPPF QGPIEVVLKD
     IGYFSLTPTG KYEYKGLYEL WVLDGIDVCI RKPLERVAED SYDKSQEGKY YIKEPVVSHT
     YVVAHNDPNP LQTVKESYEK VKERTDEILN KYNLEKFGNN MWHFKW