ID   GEP3_LACTC              Reviewed;         535 AA.
AC   C5DEU6;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Genetic interactor of prohibitins 3, mitochondrial;
DE   AltName: Full=Found in mitochondrial proteome protein 38;
DE   Flags: Precursor;
GN   Name=GEP3; Synonyms=FMP48; OrderedLocusNames=KLTH0D09878g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: May be involved in the mitochondrial lipid metabolism.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
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DR   EMBL; CU928168; CAR22701.1; -; Genomic_DNA.
DR   RefSeq; XP_002553139.1; XM_002553093.1.
DR   AlphaFoldDB; C5DEU6; -.
DR   SMR; C5DEU6; -.
DR   STRING; 559295.C5DEU6; -.
DR   EnsemblFungi; CAR22701; CAR22701; KLTH0D09878g.
DR   GeneID; 8295378; -.
DR   KEGG; lth:KLTH0D09878g; -.
DR   eggNOG; ENOG502S0UP; Eukaryota.
DR   HOGENOM; CLU_025792_1_0_1; -.
DR   InParanoid; C5DEU6; -.
DR   OMA; QIVKYIP; -.
DR   OrthoDB; 612803at2759; -.
DR   Proteomes; UP000002036; Chromosome D.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..38
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           39..535
FT                   /note="Genetic interactor of prohibitins 3, mitochondrial"
FT                   /id="PRO_0000409636"
FT   DOMAIN          111..283
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
SQ   SEQUENCE   535 AA;  60679 MW;  5F9E39C577B722FA CRC64;
     MLPVSRLCVR SSLRKLVFVR FVSCTSCGVT LQNNNVRGTG FYTPPKAQIE RKRPVIEDLK
     YLLFSQDLQS LKSELSAEER PKKNKPLICK RCNDALHHNT FSKEDFRRYS MQEVYRHVPA
     GADIYHVVPL TDFPLQLNSA VLKDSRYNSA LLLSKGDQVT PDKSLLQRKA PQFFKDMLRL
     KMNYNSNKSI AFSASKGWNI QSVYSVLRSN SFLIGCPNSG KSTLVNALLK KFPSLKPSEG
     NNASEAEIVR GAGVSNIPNM TRDLQSYNIG SKVINDLPGY STNYGSPGPE DALDAKVLEK
     IQKTHLFKKT KLVKQRYTSL KGTDAGRCYT VSGIFYLVPP PDTINQVVNY IPGNERQYRN
     IDKALSVVNS EHACPEKGPL RQYVGVQKAM ESKDNYVRHV LPPFQGSIEV VLKEIGYFQL
     KTTGKYKFLG LHEVWVPKGV DVCIREPIAR LIDEGYEGYL SSEGKKKAIP EKREVFSATY
     PMSFEETDTL QKMKEMFLER TKNDVLARKF ISSNPLKIIG TAQKEAPNLY WYYKW