ID   GEP3_LODEL              Reviewed;         665 AA.
AC   A5E047;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Genetic interactor of prohibitins 3, mitochondrial;
DE   AltName: Full=Found in mitochondrial proteome protein 38;
DE   Flags: Precursor;
GN   Name=GEP3; Synonyms=FMP48; ORFNames=LELG_02984;
OS   Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS   1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC   Lodderomyces.
OX   NCBI_TaxID=379508;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC   YB-4239;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: May be involved in the mitochondrial lipid metabolism.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
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DR   EMBL; CH981526; EDK44805.1; -; Genomic_DNA.
DR   RefSeq; XP_001526426.1; XM_001526376.1.
DR   AlphaFoldDB; A5E047; -.
DR   SMR; A5E047; -.
DR   STRING; 379508.A5E047; -.
DR   PRIDE; A5E047; -.
DR   EnsemblFungi; EDK44805; EDK44805; LELG_02984.
DR   GeneID; 5233512; -.
DR   KEGG; lel:LELG_02984; -.
DR   VEuPathDB; FungiDB:LELG_02984; -.
DR   eggNOG; ENOG502S067; Eukaryota.
DR   HOGENOM; CLU_025792_0_0_1; -.
DR   InParanoid; A5E047; -.
DR   OMA; HYLYESI; -.
DR   OrthoDB; 612803at2759; -.
DR   Proteomes; UP000001996; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..17
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..665
FT                   /note="Genetic interactor of prohibitins 3, mitochondrial"
FT                   /id="PRO_0000409637"
FT   DOMAIN          185..380
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
SQ   SEQUENCE   665 AA;  75759 MW;  FF1F411A69A28DD3 CRC64;
     MISRLIHSKH YLTLFRQNSS IAIPLLYSLE LRCRSCGIKV QDKNKDEPGY YIKPVKLLND
     SKTFSEQTQK LGLVVAADAP NILQNPIKKR PLDEAYDKLI SKMSQSDKDL LINDFTLFGQ
     PKYKDSKELE TIPKNDKGET VKEVVNKIYT VKPDETSVEC MRCRNIQYQS SYKMTDENFP
     ISEMEQVLQN LPRASTAPLV YLFNANDFPM GINPNIFKFR NPKDIYFIMT KTDNLVADIK
     NKFNKSAILH EYTKNFVSDY LGIKYGVPKQ NIFLSSSLKG WKLDELHRFI PDGSYIIGNT
     NCGKSTMIKS LMLNEELQNK KEQVRHVPFN TVSKIKDKFK QQFYQKVGPG VSYLPGFTRD
     IIPLNIGLKT VYDVPGFSSS PKIHYLYESI KEPKIIHRLI KGEKTFAKGY NGAQYKSFKG
     PQVLCFEGLG YLQLPKDCLF QIRNVTNFKI HAFSNIDKAA KLAQNIPPSL ANDFAIGNHS
     LFSQFDKYLV PPFYGSIELV FENFGYIHIK PIGAKQSNEL MKLYLYPGLQ SIIRQPIINY
     ITKTPTGFDK YGNALMKYDP VYKSEFALKR FRGGEEYQPL FSRLIPCVED IEKFVGGGGG
     GAVAAAGAAA GAAETNIVDG NDAQGLAQSL RSQEYLQLNQ FLKRRAKYDE SYYMDASNKY
     DFWVE