ID   GEP5_CANGA              Reviewed;         278 AA.
AC   Q6FKE0;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Genetic interactor of prohibitin 5, mitochondrial;
DE   AltName: Full=Required for respiratory growth protein 5;
GN   Name=GEP5; Synonyms=RRG5; OrderedLocusNames=CAGL0L12320g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Essential for respiratory growth and required for maintenance
CC       of mtDNA. Required for cell survival in the absence of prohibitins (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GEP5 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR380958; CAG62278.1; -; Genomic_DNA.
DR   RefSeq; XP_449304.1; XM_449304.1.
DR   AlphaFoldDB; Q6FKE0; -.
DR   SMR; Q6FKE0; -.
DR   EnsemblFungi; CAG62278; CAG62278; CAGL0L12320g.
DR   GeneID; 2890694; -.
DR   KEGG; cgr:CAGL0L12320g; -.
DR   CGD; CAL0136046; CAGL0L12320g.
DR   VEuPathDB; FungiDB:CAGL0L12320g; -.
DR   HOGENOM; CLU_1001149_0_0_1; -.
DR   InParanoid; Q6FKE0; -.
DR   Proteomes; UP000002428; Chromosome L.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..278
FT                   /note="Genetic interactor of prohibitin 5, mitochondrial"
FT                   /id="PRO_0000399684"
SQ   SEQUENCE   278 AA;  32445 MW;  08AD9BCBABA3BC6E CRC64;
     MSGRVLEVFR GLPLLPLSHE IVARCWDRMV RQRDVYYQFA VHVSHCHERL STRNLLRLVT
     HVHHVLAPMN ELPAHLRQYQ SEYHALVASW PTVTERQILD AMELGKGMAV RIPHNKTLRQ
     MFEQHEWLVQ QRLLDDKRLK RRRLLRCEVQ MATPTTNGST NGNTNGSEIS FRQCPLTIRE
     LTPLGALESE AKFKNRVRSD VHSLWRLLAV QHPPLSRPHA DELVRTLKRT LGTSRTDRSI
     ARAYLQLLQR AYTYTYTYTD TEAEAQLQYS RVSQLVSH