ID   GEP5_YEAS1              Reviewed;         293 AA.
AC   B3LT59;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Genetic interactor of prohibitin 5, mitochondrial;
DE   AltName: Full=Required for respiratory growth protein 5;
GN   Name=GEP5; Synonyms=RRG5; ORFNames=SCRG_05075;
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a;
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential for respiratory growth and required for maintenance
CC       of mtDNA. Required for cell survival in the absence of prohibitins (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GEP5 family. {ECO:0000305}.
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DR   EMBL; CH408054; EDV09394.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3LT59; -.
DR   EnsemblFungi; EDV09394; EDV09394; SCRG_05075.
DR   HOGENOM; CLU_079415_0_0_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IEA:InterPro.
DR   InterPro; IPR031455; Gep5.
DR   Pfam; PF17053; GEP5; 1.
PE   3: Inferred from homology;
KW   Mitochondrion.
FT   CHAIN           1..293
FT                   /note="Genetic interactor of prohibitin 5, mitochondrial"
FT                   /id="PRO_0000399688"
SQ   SEQUENCE   293 AA;  33882 MW;  6BF3784A4FDF2672 CRC64;
     MASQVNALLL PVIESTPLHQ ITKVALTTTL TSKQSDYKFK EIAVPLTKSL QLYEKAQRRQ
     DLRASLKALE SIIYQTHFQW NNPLPRHAHL FQKHYHFLLT HWPFENHRDL VDSIAVNNGK
     LNSTSSRSVW LKADWITLFN VKNPWVQTPP SLMRLSGTDL DTFTPERIFL INSLGNHYKF
     LIANSHLSYN HKKYPSPGVQ IPIRNALGEV SPAKQIAQLF ARQLSHIYKS LFIENPPLSP
     ENELALTAVF YDETVERRLR RLYMRACARA YTTTNADSTT EPLMFHCTRW EVD