ID   GEP5_YEAS7              Reviewed;         293 AA.
AC   A7A0Z5;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=Genetic interactor of prohibitin 5, mitochondrial;
DE   AltName: Full=Required for respiratory growth protein 5;
GN   Name=GEP5; Synonyms=RRG5; ORFNames=SCY_3669;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Essential for respiratory growth and required for maintenance
CC       of mtDNA. Required for cell survival in the absence of prohibitins (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GEP5 family. {ECO:0000305}.
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DR   EMBL; AAFW02000167; EDN59636.1; -; Genomic_DNA.
DR   AlphaFoldDB; A7A0Z5; -.
DR   EnsemblFungi; EDN59636; EDN59636; SCY_3669.
DR   HOGENOM; CLU_079415_0_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IEA:InterPro.
DR   InterPro; IPR031455; Gep5.
DR   Pfam; PF17053; GEP5; 1.
PE   3: Inferred from homology;
KW   Mitochondrion.
FT   CHAIN           1..293
FT                   /note="Genetic interactor of prohibitin 5, mitochondrial"
FT                   /id="PRO_0000399690"
SQ   SEQUENCE   293 AA;  33850 MW;  6BF3694B53692BC5 CRC64;
     MASQVNALLL PVIESTPLHQ ITKVALTTTL TSKQSDYKFK EIAVPLTKSL QLYEKAQRRQ
     DLRASLKALE SIIYQTHFQW NNPLPRHAHL FQKHYHFLLT HWPFENHRDL VDSIAVNNGK
     LNSTSSRSVW LKADWITLFN VKNPWVQTPP SLVRLSGTDL DTFTPERIFL INSLGNHYKF
     LIANSHLSYN HKKYPSPGVQ IPIRNALGEV SPAKQIAQLF ARQLSHIYKS LFIENPPLSP
     ENELALTAVF YDETVERRLR RLYMRACARA YTTTNADSTT EPLMFHCTRW EVD