ID   GEP5_YEAS8              Reviewed;         293 AA.
AC   C8ZD61;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Genetic interactor of prohibitin 5, mitochondrial;
DE   AltName: Full=Required for respiratory growth protein 5;
GN   Name=GEP5; Synonyms=RRG5; ORFNames=EC1118_1L10_1695g;
OS   Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=643680;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin EC1118 / Prise de mousse;
RX   PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA   Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA   Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT   "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT   sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC   -!- FUNCTION: Essential for respiratory growth and required for maintenance
CC       of mtDNA. Required for cell survival in the absence of prohibitins (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GEP5 family. {ECO:0000305}.
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DR   EMBL; FN393078; CAY81327.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8ZD61; -.
DR   EnsemblFungi; CAY81327; CAY81327; EC1118_1L10_1695g.
DR   HOGENOM; CLU_079415_0_0_1; -.
DR   Proteomes; UP000000286; Chromosome XII, Scaffold EC1118_1L10.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IEA:InterPro.
DR   InterPro; IPR031455; Gep5.
DR   Pfam; PF17053; GEP5; 1.
PE   3: Inferred from homology;
KW   Mitochondrion.
FT   CHAIN           1..293
FT                   /note="Genetic interactor of prohibitin 5, mitochondrial"
FT                   /id="PRO_0000399691"
SQ   SEQUENCE   293 AA;  33882 MW;  6BF3784A4FDF2672 CRC64;
     MASQVNALLL PVIESTPLHQ ITKVALTTTL TSKQSDYKFK EIAVPLTKSL QLYEKAQRRQ
     DLRASLKALE SIIYQTHFQW NNPLPRHAHL FQKHYHFLLT HWPFENHRDL VDSIAVNNGK
     LNSTSSRSVW LKADWITLFN VKNPWVQTPP SLMRLSGTDL DTFTPERIFL INSLGNHYKF
     LIANSHLSYN HKKYPSPGVQ IPIRNALGEV SPAKQIAQLF ARQLSHIYKS LFIENPPLSP
     ENELALTAVF YDETVERRLR RLYMRACARA YTTTNADSTT EPLMFHCTRW EVD