ID   GEP7_YEAS1              Reviewed;         287 AA.
AC   B3LHC6;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 26.
DE   RecName: Full=Genetic interactor of prohibitin 7, mitochondrial;
DE   Flags: Precursor;
GN   Name=GEP7; ORFNames=SCRG_01059;
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a;
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in respiratory growth and required for cell survival
CC       in the absence of prohibitins or GEM1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GEP7 family. {ECO:0000305}.
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DR   EMBL; CH408044; EDV10284.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3LHC6; -.
DR   EnsemblFungi; EDV10284; EDV10284; SCRG_01059.
DR   HOGENOM; CLU_064141_0_0_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Transit peptide; Transmembrane;
KW   Transmembrane helix.
FT   TRANSIT         1..24
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..287
FT                   /note="Genetic interactor of prohibitin 7, mitochondrial"
FT                   /id="PRO_0000399740"
FT   TRANSMEM        250..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   287 AA;  32959 MW;  18DF55D2B5CF1FA5 CRC64;
     MVLSNVKIFR LKSHRAFRIG PMIKAVAGNL LVKRFYQPKL ERIPPASLLL KQKIRLAQNG
     STTSTENPIS FSQTMSEIFS VLQPSAPDLD EDETSGLKRD HLLTERLNNG ELGVIMNKFF
     NPSSTHNNQL IDTNILLQNF PKLSGNDLDL LDFAINEKMR GNWNDLKQDF IQLWYYKSFG
     FLGPRTQFVL TNSSPSLRSQ FLKLPFIEYN WFLLQNNKNA NILPADVQNV VKVFHLDDKR
     FSWKSIDPFS KAIISFVVFV SIYVWLDESA KQKTKELPAQ KSTVISE