ID   GEP7_YEAS7              Reviewed;         287 AA.
AC   A6ZUB9;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 29.
DE   RecName: Full=Genetic interactor of prohibitin 7, mitochondrial;
DE   Flags: Precursor;
GN   Name=GEP7; ORFNames=SCY_2002;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Involved in respiratory growth and required for cell survival
CC       in the absence of prohibitins or GEM1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GEP7 family. {ECO:0000305}.
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DR   EMBL; AAFW02000099; EDN62057.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZUB9; -.
DR   EnsemblFungi; EDN62057; EDN62057; SCY_2002.
DR   HOGENOM; CLU_064141_0_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Transit peptide; Transmembrane;
KW   Transmembrane helix.
FT   TRANSIT         1..24
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..287
FT                   /note="Genetic interactor of prohibitin 7, mitochondrial"
FT                   /id="PRO_0000399743"
FT   TRANSMEM        250..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   287 AA;  32960 MW;  6E4D0C695FB82AE0 CRC64;
     MVLSNVKIFR LKSHRAFRIG PMIKAVAGNL LVKRFYQPKL ERIPPASLLL KQKIRLAQNG
     STTSTENPIS FSQTMSEIFS VLQPSAPDLD EDKTSGLKRD HLLTERLNNG ELGVIMNKFF
     NPSSTHNNQL IDTNILLQNF PKLSGNDLDL LDFAINEKMR GNWNDLKQDF IQLWYYKSFG
     FLGPRTQFVL TNSSPSLRSQ FLKLPFTEYN WFLLQNNKNA NILPADVQNV VKVFHLDDKR
     FTWKSIDPFS KAIISFVVFV SIYVWLDESA KQKTKELPAQ KSTVISE