GEP7_ZYGRC
ID GEP7_ZYGRC Reviewed; 258 AA.
AC C5DT30;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=Genetic interactor of prohibitin 7, mitochondrial;
DE Flags: Precursor;
GN Name=GEP7; OrderedLocusNames=ZYRO0C04972g;
OS Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS / NRRL Y-229) (Candida mogii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX NCBI_TaxID=559307;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC Y-229;
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- FUNCTION: Involved in respiratory growth and required for cell survival
CC in the absence of prohibitins. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Single-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GEP7 family. {ECO:0000305}.
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DR EMBL; CU928175; CAR26941.1; -; Genomic_DNA.
DR RefSeq; XP_002495874.1; XM_002495829.1.
DR AlphaFoldDB; C5DT30; -.
DR SMR; C5DT30; -.
DR EnsemblFungi; CAR26941; CAR26941; ZYRO0C04972g.
DR GeneID; 8203070; -.
DR KEGG; zro:ZYRO0C04972g; -.
DR HOGENOM; CLU_094335_0_0_1; -.
DR InParanoid; C5DT30; -.
DR Proteomes; UP000008536; Chromosome C.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Reference proteome; Transit peptide;
KW Transmembrane; Transmembrane helix.
FT TRANSIT 1..15
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 16..258
FT /note="Genetic interactor of prohibitin 7, mitochondrial"
FT /id="PRO_0000399745"
FT TRANSMEM 221..238
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 258 AA; 29749 MW; A0A349667BC941DD CRC64;
MSQYRFPIRI LTRFYTQASS RLPPKSLLIK QADRIRRSKD GQADGSKLMV SSLKDIASMF
QANAETPEDE EREILNQQNY LRQQIESGEL ERLLQDKFNL DESISLMSTN LLVQQFPKLN
AQQVELIQEA VSMDSNKHWN EIPQYMKQLQ FYFAFGSHGP RLSIPFNSRE KPLDFAFKIP
SPVTTDGQTK IHKLKPSHLV NLHTITDQRS KIFQTTKLDP ATRCILWSAI LVSIVFGVQE
WRLQQDPQAK ITVLSNSV