GERBA_BACSU
ID GERBA_BACSU Reviewed; 483 AA.
AC P39569;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 2.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Spore germination protein B1;
GN Name=gerBA; OrderedLocusNames=BSU35800;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=8012571; DOI=10.1099/00221287-140-3-471;
RA Corfe B.M., Sammons R.L., Smith D.A., Maueel C.;
RT "The gerB region of the Bacillus subtilis 168 chromosome encodes a
RT homologue of the gerA spore germination operon.";
RL Microbiology 140:471-478(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP SEQUENCE REVISION TO 439-448.
RX PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT 168 reference genome a decade later.";
RL Microbiology 155:1758-1775(2009).
CC -!- FUNCTION: Involved in the response to the germinative mixture of L-
CC asparagine, glucose, fructose and potassium ions (AGFK). Cannot
CC stimulate germination in the absence of gerD and gerK gene products
CC (fructose and glucose receptors respectively).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Expressed in the forespore compartment of the
CC developing sporangium.
CC -!- SIMILARITY: Belongs to the GerABKA family. {ECO:0000305}.
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DR EMBL; L16960; AAA22466.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB15597.2; -; Genomic_DNA.
DR PIR; I39855; I39855.
DR RefSeq; NP_391461.2; NC_000964.3.
DR RefSeq; WP_003243291.1; NZ_JNCM01000034.1.
DR AlphaFoldDB; P39569; -.
DR SMR; P39569; -.
DR STRING; 224308.BSU35800; -.
DR TCDB; 9.A.11.1.2; the dipicolinic acid transporter (dpa-t) family.
DR PaxDb; P39569; -.
DR PRIDE; P39569; -.
DR EnsemblBacteria; CAB15597; CAB15597; BSU_35800.
DR GeneID; 936814; -.
DR KEGG; bsu:BSU35800; -.
DR PATRIC; fig|224308.179.peg.3876; -.
DR eggNOG; COG0697; Bacteria.
DR InParanoid; P39569; -.
DR OMA; QPGQDLK; -.
DR PhylomeDB; P39569; -.
DR BioCyc; BSUB:BSU35800-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009847; P:spore germination; IEA:InterPro.
DR InterPro; IPR004995; Spore_Ger.
DR Pfam; PF03323; GerA; 1.
DR PIRSF; PIRSF005690; GerBA; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Germination; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..483
FT /note="Spore germination protein B1"
FT /id="PRO_0000164015"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 353..373
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 375..395
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 410..430
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 439..448
FT /note="FGQDYIIPIM -> LARITLSDH (in Ref. 1; AAA22466)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 483 AA; 53962 MW; 2D563D3D4A6A95EB CRC64;
MQIDSDLQNN LDTLKKTLGQ NDDMMFYTFA FGDSRQKACL LYIDGLTENK MLAQYVISPL
QKEALAHKEC SIEDLSAFFF GFHHSVVSTM KEIEQLVFSG QAILLADGYR GGLAFDTKSV
ATRSLDEPSS EVVERGPKIG FIEKLRTNTA LLRERTSDPN LVIKEMTLGK RTKKKIAVAY
IQDIAPDYVV KEVFKRLKSV NIDNLPESGT LEQLIEDEPF SIFPTILSTE RPDRVESSLL
EGRVSILVDG TPFALIVPAT VDEFIHSPDD YSQRWIPMSL VRLLRYSSIL ITIYLPGLYI
SLVSFHTGLL PTRMAISIAG SRLNVPFPPF VEAFIMIFTI ELIREAGLRL PKPIGQTIGL
IGGVVIGQAA VQAQIVSALM VIVVSVTALA SFTVPSYAYN FPLRIIRIGV MISATALGMY
GVIMVYLFVI GHLMRLKSFG QDYIIPIMAQ PGQDLKDTVI RIPTMFLKRR PTRNDPEDNI
RQR
