GERD_BACSU
ID GERD_BACSU Reviewed; 185 AA.
AC P16450;
DT 01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1990, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Spore germination protein GerD;
DE Flags: Precursor;
GN Name=gerD; OrderedLocusNames=BSU01550;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=2517635; DOI=10.1099/00221287-135-12-3431;
RA Yon J.R., Sammons R.L., Smith D.A.;
RT "Cloning and sequencing of the gerD gene of Bacillus subtilis.";
RL J. Gen. Microbiol. 135:3431-3445(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=8969501; DOI=10.1099/13500872-142-11-3039;
RA Yasumoto K., Liu H., Jeong S.M., Ohashi Y., Kakinuma S., Tanaka K.,
RA Kawamura F., Yoshikawa H., Takahashi H.;
RT "Sequence analysis of a 50 kb region between spo0H and rrnH on the Bacillus
RT subtilis chromosome.";
RL Microbiology 142:3039-3046(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-84.
RC STRAIN=168 / JH642;
RX PubMed=8576055; DOI=10.1128/jb.178.4.1178-1186.1996;
RA Dartois V., Djavakhishvili T., Hoch J.A.;
RT "Identification of a membrane protein involved in activation of the KinB
RT pathway to sporulation in Bacillus subtilis.";
RL J. Bacteriol. 178:1178-1186(1996).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 147-185.
RX PubMed=7559346; DOI=10.1128/jb.177.19.5582-5589.1995;
RA Sekiguchi J., Akeo K., Yamamoto H., Khasanov F.K., Alonso J.C., Kuroda A.;
RT "Nucleotide sequence and regulation of a new putative cell wall hydrolase
RT gene, cwlD, which affects germination in Bacillus subtilis.";
RL J. Bacteriol. 177:5582-5589(1995).
CC -!- FUNCTION: May be involved in fructose recognition during germination.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Active between T2 and T6 of sporulation.
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DR EMBL; M27259; AAA22470.1; -; Genomic_DNA.
DR EMBL; D64126; BAA10995.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB11931.1; -; Genomic_DNA.
DR EMBL; U23797; AAC43999.1; -; Genomic_DNA.
DR EMBL; X74737; CAA52757.1; -; Genomic_DNA.
DR PIR; A37207; A37207.
DR RefSeq; NP_388036.1; NC_000964.3.
DR RefSeq; WP_003235126.1; NZ_CP053102.1.
DR AlphaFoldDB; P16450; -.
DR SMR; P16450; -.
DR STRING; 224308.BSU01550; -.
DR PaxDb; P16450; -.
DR PRIDE; P16450; -.
DR DNASU; 938910; -.
DR EnsemblBacteria; CAB11931; CAB11931; BSU_01550.
DR GeneID; 938910; -.
DR KEGG; bsu:BSU01550; -.
DR PATRIC; fig|224308.179.peg.159; -.
DR eggNOG; ENOG5032TXD; Bacteria.
DR OMA; MKDPEYQ; -.
DR BioCyc; BSUB:BSU01550-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IDA:CACAO.
DR GO; GO:0031160; C:spore wall; IDA:CACAO.
DR InterPro; IPR041262; GerD_central.
DR Pfam; PF17898; GerD; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Germination; Lipoprotein; Membrane; Palmitate;
KW Reference proteome; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 20..185
FT /note="Spore germination protein GerD"
FT /id="PRO_0000018177"
FT LIPID 20
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 20
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
SQ SEQUENCE 185 AA; 21117 MW; 4F37211BDF61B340 CRC64;
MSKAKTLLMS CFLLLSVTAC APKDQAADMD YDQTKKMVVD ILKTDDGKKA IKELLNDDAM
NEALVIDQDA IKGTIEKTLT SKKGEEFWKN IFEDTDFAEG FAKTLQTEHE KVIKKLMKDP
DYQKMLMSVM QDPGMDKKYS QLAKSQEFRS YLEEVINETL SSPLYKKQFE DELKKAAKDT
AKESE
