ID   GERIA_BACCE             Reviewed;         663 AA.
AC   O85467;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Spore germination protein GerIA;
GN   Name=gerIA;
OS   Bacillus cereus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1396;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 10876 / DSM 9378 / NRRL B-569;
RX   PubMed=9852021; DOI=10.1128/jb.180.24.6729-6735.1998;
RA   Clements M.O., Moir A.;
RT   "Role of the gerI operon of Bacillus cereus 569 in the response of spores
RT   to germinants.";
RL   J. Bacteriol. 180:6729-6735(1998).
CC   -!- FUNCTION: Required for inosine germination.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GerABKA family. {ECO:0000305}.
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DR   EMBL; AF067645; AAD03541.1; -; Genomic_DNA.
DR   AlphaFoldDB; O85467; -.
DR   SMR; O85467; -.
DR   STRING; 1396.DJ87_140; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009847; P:spore germination; IEA:InterPro.
DR   InterPro; IPR004995; Spore_Ger.
DR   Pfam; PF03323; GerA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Germination; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..663
FT                   /note="Spore germination protein GerIA"
FT                   /id="PRO_0000164017"
FT   TRANSMEM        414..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        451..471
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        491..511
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        541..561
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        578..598
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..59
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..124
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..172
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   663 AA;  75311 MW;  DAD65C52422B7025 CRC64;
     MIWNWLRKKK KSNTSKLNET DNQEQHSNNQ EDDNKEQTRS MKHNKGKNNE QKDSSQDKQQ
     SAKQGDSSQD KQQNPKQEDS SQDKQQNPKQ GDSSQDKQQS AKQKDPSQDK QQNPKQEDSS
     QDKQQSAKQG DSSQDKQQSA KQGDSSQDKQ QNAKQDEPSQ SKQQSSGGNS IYDFTKPEKD
     RIHSLQNLIE KLKKSSDFVN YHTSDDETMP YWISYYRPSL DGEKLQKYLM PTLLERPNAS
     LEELKEHIPM SGITITNDLQ KIEDMVLKGH AIIQLNQQDQ KCMLANIAID NYRAPTPPLN
     ESTVIGPQEG FVEDIDTNIN LVRKRLPVLD LQTKEMIIGE FSKTKVVMMY LDNLAEKDNV
     DFLEESLRAL EYDQINDSAY LQELMGEKSI FPLYINTERT DRVTKALIDG KIAIFVDGSP
     SVLLTPVSYF DFFISPEDYN VSWMYATFSR ILRLIAVLFS ICATPLYVAV LNYHYELIPS
     DLLETLILSR AQVPFPPLIE ALFLELAIDL LREAGARLPM KVGQTLGIVG GIVIGQASVQ
     AGLTSNILLI IVALSALASF ITPIYKMGNA VRLLRFPFLA FAEIGGLFGI SLGFIFLFTH
     LFRLTSLRKP YALFYPTRQQ SVKDSWIRFP LTMIDTRDVQ ARPQHVKKAA KGISTKHRSD
     FDD