GERKB_BACSU
ID GERKB_BACSU Reviewed; 373 AA.
AC P49940;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Spore germination protein KB;
GN Name=gerKB; OrderedLocusNames=BSU03720;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RA Irie R., Fujita Y.Y.F., Kobayasi M.;
RT "Nucleotide sequence and gene organization of the gerK spore germinating
RT locus of Bacillus subtilis 168.";
RL Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=8969502; DOI=10.1099/13500872-142-11-3047;
RA Yamane K., Kumano M., Kurita K.;
RT "The 25 degrees-36 degrees region of the Bacillus subtilis chromosome:
RT determination of the sequence of a 146 kb segment and identification of 113
RT genes.";
RL Microbiology 142:3047-3056(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- FUNCTION: Involved in the germination response to the combination of
CC glucose, fructose, L-asparagine, and KCl.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
CC {ECO:0000305}.
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DR EMBL; D78187; BAA11256.1; -; Genomic_DNA.
DR EMBL; D50453; BAA09004.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB12180.1; -; Genomic_DNA.
DR PIR; I39860; I39860.
DR RefSeq; NP_388254.1; NC_000964.3.
DR RefSeq; WP_003234509.1; NZ_JNCM01000031.1.
DR AlphaFoldDB; P49940; -.
DR SMR; P49940; -.
DR STRING; 224308.BSU03720; -.
DR TCDB; 2.A.3.9.3; the amino acid-polyamine-organocation (apc) family.
DR PaxDb; P49940; -.
DR PRIDE; P49940; -.
DR EnsemblBacteria; CAB12180; CAB12180; BSU_03720.
DR GeneID; 938282; -.
DR KEGG; bsu:BSU03720; -.
DR PATRIC; fig|224308.179.peg.392; -.
DR eggNOG; COG1457; Bacteria.
DR InParanoid; P49940; -.
DR OMA; YILYFAY; -.
DR PhylomeDB; P49940; -.
DR BioCyc; BSUB:BSU03720-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009847; P:spore germination; IEA:InterPro.
DR InterPro; IPR004761; Spore_GerAB.
DR PANTHER; PTHR34975; PTHR34975; 1.
DR Pfam; PF03845; Spore_permease; 1.
DR TIGRFAMs; TIGR00912; 2A0309; 1.
PE 3: Inferred from homology;
KW Cell membrane; Germination; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..373
FT /note="Spore germination protein KB"
FT /id="PRO_0000087464"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 269..289
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 373 AA; 41770 MW; 6B97E3A520DC98BF CRC64;
MEKARISIRQ LFVMIIIFEL GSSLLITPGS MAGRDAWIAV LLGCAIGLFL FYLYQGIYQC
YPNSSPKEYM DDMLGTKLSW LFSFLYILYF AYIAARVLRD FGEMLLTFAY HDTPIIIVNA
LLMVVSIYAV RKGIEVLARA AELLFGAMYL LGAIGLVLII VSGTIDPHNL KPVLANGISP
VLHSVFTQTM YVPFGEVVLF VMIFPNLNDR KDVKKMGMIA MAISGLIVAL TVAINISVLD
VDLTLRSQFP LLSTIQTIKV EEFLDRLDVF FMLALIIGGF FKVSLYLYAT VVGTSTLFKE
KNPSQLAYPM GLGILILSIT IATNFSEHLN EGLNVVPLYI HLPFQLLFPL FLFIVAVWKK
KRREKSKGEE AKK
