ID   GERKC_BACSU             Reviewed;         407 AA.
AC   P49941;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Spore germination protein KC;
DE   Flags: Precursor;
GN   Name=gerKC; OrderedLocusNames=BSU03710;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Irie R., Fujita Y.Y.F., Kobayasi M.;
RT   "Nucleotide sequence and gene organization of the gerK spore germinating
RT   locus of Bacillus subtilis 168.";
RL   Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=8969502; DOI=10.1099/13500872-142-11-3047;
RA   Yamane K., Kumano M., Kurita K.;
RT   "The 25 degrees-36 degrees region of the Bacillus subtilis chromosome:
RT   determination of the sequence of a 146 kb segment and identification of 113
RT   genes.";
RL   Microbiology 142:3047-3056(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Involved in the germination response to the combination of
CC       glucose, fructose, L-asparagine, and KCl.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GerABKC lipoprotein family. {ECO:0000305}.
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DR   EMBL; D78187; BAA11255.1; -; Genomic_DNA.
DR   EMBL; D50453; BAA09003.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12179.1; -; Genomic_DNA.
DR   PIR; I39859; I39859.
DR   RefSeq; NP_388253.1; NC_000964.3.
DR   RefSeq; WP_003246578.1; NZ_JNCM01000031.1.
DR   AlphaFoldDB; P49941; -.
DR   SMR; P49941; -.
DR   STRING; 224308.BSU03710; -.
DR   PaxDb; P49941; -.
DR   PRIDE; P49941; -.
DR   EnsemblBacteria; CAB12179; CAB12179; BSU_03710.
DR   GeneID; 938287; -.
DR   KEGG; bsu:BSU03710; -.
DR   PATRIC; fig|224308.179.peg.391; -.
DR   eggNOG; ENOG502Z9N7; Bacteria.
DR   InParanoid; P49941; -.
DR   OMA; YYSHTNL; -.
DR   PhylomeDB; P49941; -.
DR   BioCyc; BSUB:BSU03710-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009847; P:spore germination; IEA:InterPro.
DR   Gene3D; 3.30.300.210; -; 1.
DR   InterPro; IPR008844; Spore_GerAC.
DR   InterPro; IPR038501; Spore_GerAC_C_sf.
DR   Pfam; PF05504; Spore_GerAC; 1.
DR   TIGRFAMs; TIGR02887; spore_ger_x_C; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Germination; Lipoprotein; Membrane; Palmitate;
KW   Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..407
FT                   /note="Spore germination protein KC"
FT                   /id="PRO_0000018175"
FT   LIPID           21
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           21
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   407 AA;  45836 MW;  E715F96C8197A26E CRC64;
     MVRKCLLAVL MLLSVIVLPG CWDKRELTDL AIISAIGIDR TNDSNYVLHL QIINPGNVAG
     GLQGGGAGDR PPVSVYSIEG NNITEALRKA SMKVSRRLYF AHTNLVVINE KLAKEEGLDF
     VLDNLDRDTE FRTTATFVVA HKTKAENIVK ILTPIDKIPS NKVNKTLDFT EAQYGRVVKI
     NIQDVLKTLA ANTMAPVIPG YMMIGDDKKG VSMENTQATD PKAILQADGL AVFDKAGYLK
     YWLEDDESVG AVWLMNKIQH TFINADWGKT KDAVSLQVTH QDTKLVPKMR NGRPYIHVKV
     SVEGIIDAVK YPFQLSDPKV LAAIEKALNK ELEKEISHTV KKIKKNKIDF IGFGDTIYRK
     YPEQWEKMKD TWDKEYLPEL PIDVKAETYI RRTGLRNNPI KHQFKDD