ID   GERPA_BACSU             Reviewed;          73 AA.
AC   O06721;
DT   26-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Probable spore germination protein GerPA;
GN   Name=gerPA; Synonyms=yisH; OrderedLocusNames=BSU10720;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9353931; DOI=10.1099/00221287-143-10-3305;
RA   Medina N., Vannier F., Roche B., Autret S., Levine A., Seror S.J.;
RT   "Sequencing of regions downstream of addA (98 degrees) and citG (289
RT   degrees) in Bacillus subtilis.";
RL   Microbiology 143:3305-3308(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   CHARACTERIZATION.
RC   STRAIN=168 / 1604;
RX   PubMed=10715007; DOI=10.1128/jb.182.7.1987-1994.2000;
RA   Behravan J., Chirakkal H., Masson A., Moir A.;
RT   "Mutations in the gerP locus of Bacillus subtilis and Bacillus cereus
RT   affect access of germinants to their targets in spores.";
RL   J. Bacteriol. 182:1987-1994(2000).
CC   -!- FUNCTION: Required for the formation of functionally normal spores.
CC       Could be involved in the establishment of normal spore coat structure
CC       and/or permeability, which allows the access of germinants to their
CC       receptor.
CC   -!- DEVELOPMENTAL STAGE: Expressed during sporulation, around the time of
CC       spore coat synthesis and assembly, in mother cell compartment.
CC   -!- INDUCTION: Expression is sigma K-dependent and negatively regulated by
CC       GerE.
CC   -!- SIMILARITY: Belongs to the GerPA/GerPF family. {ECO:0000305}.
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DR   EMBL; Y09476; CAA70679.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12912.1; -; Genomic_DNA.
DR   PIR; H69836; H69836.
DR   RefSeq; NP_388953.1; NC_000964.3.
DR   RefSeq; WP_003233088.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; O06721; -.
DR   STRING; 224308.BSU10720; -.
DR   PaxDb; O06721; -.
DR   EnsemblBacteria; CAB12912; CAB12912; BSU_10720.
DR   GeneID; 936348; -.
DR   KEGG; bsu:BSU10720; -.
DR   PATRIC; fig|224308.179.peg.1152; -.
DR   eggNOG; ENOG50332FH; Bacteria.
DR   OMA; IHIGDCI; -.
DR   PhylomeDB; O06721; -.
DR   BioCyc; BSUB:BSU10720-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR019618; Spore_germination_GerPA.
DR   PANTHER; PTHR37808; PTHR37808; 1.
DR   Pfam; PF10676; gerPA; 1.
PE   1: Evidence at protein level;
KW   Germination; Reference proteome; Sporulation.
FT   CHAIN           1..73
FT                   /note="Probable spore germination protein GerPA"
FT                   /id="PRO_0000105870"
SQ   SEQUENCE   73 AA;  7541 MW;  8D9EE207B2FC4864 CRC64;
     MPAIVGAFKI NAIGTSGVVH IGDCITISPQ AQVRTFAGAG SFNTGDSLKV MNYQNATNVY
     DNDAVDQPIV ANA