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GERPC_BACSU
ID   GERPC_BACSU             Reviewed;         205 AA.
AC   O06719;
DT   26-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Probable spore germination protein GerPC;
GN   Name=gerPC; Synonyms=yisF; OrderedLocusNames=BSU10700;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9353931; DOI=10.1099/00221287-143-10-3305;
RA   Medina N., Vannier F., Roche B., Autret S., Levine A., Seror S.J.;
RT   "Sequencing of regions downstream of addA (98 degrees) and citG (289
RT   degrees) in Bacillus subtilis.";
RL   Microbiology 143:3305-3308(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   CHARACTERIZATION.
RC   STRAIN=168 / 1604;
RX   PubMed=10715007; DOI=10.1128/jb.182.7.1987-1994.2000;
RA   Behravan J., Chirakkal H., Masson A., Moir A.;
RT   "Mutations in the gerP locus of Bacillus subtilis and Bacillus cereus
RT   affect access of germinants to their targets in spores.";
RL   J. Bacteriol. 182:1987-1994(2000).
CC   -!- FUNCTION: Required for the formation of functionally normal spores.
CC       Could be involved in the establishment of normal spore coat structure
CC       and/or permeability, which allows the access of germinants to their
CC       receptor.
CC   -!- DEVELOPMENTAL STAGE: Expressed during sporulation, around the time of
CC       spore coat synthesis and assembly, in mother cell compartment.
CC   -!- INDUCTION: Expression is sigma K-dependent and negatively regulated by
CC       GerE.
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DR   EMBL; Y09476; CAA70677.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12910.1; -; Genomic_DNA.
DR   PIR; F69836; F69836.
DR   RefSeq; NP_388951.1; NC_000964.3.
DR   RefSeq; WP_003245548.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; O06719; -.
DR   STRING; 224308.BSU10700; -.
DR   PaxDb; O06719; -.
DR   PRIDE; O06719; -.
DR   EnsemblBacteria; CAB12910; CAB12910; BSU_10700.
DR   GeneID; 939327; -.
DR   KEGG; bsu:BSU10700; -.
DR   PATRIC; fig|224308.179.peg.1150; -.
DR   eggNOG; ENOG50335K6; Bacteria.
DR   OMA; IRQNVDM; -.
DR   BioCyc; BSUB:BSU10700-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR019673; Spore_germination_GerPC.
DR   Pfam; PF10737; GerPC; 1.
PE   1: Evidence at protein level;
KW   Germination; Reference proteome; Sporulation.
FT   CHAIN           1..205
FT                   /note="Probable spore germination protein GerPC"
FT                   /id="PRO_0000087470"
SQ   SEQUENCE   205 AA;  24240 MW;  C5060B92C8CB0021 CRC64;
     MYDQSVSSYL QNLNSFVQQQ AIHIQQLERQ LKEIQTEMNT MKQRPATTIE RVEYKFDQLK
     IERLDGTLNI GLNPTDPNSV QNFDVSQSTP QIGMMQQEES AQLMQQIRQN VDMYLTEEIP
     DILEQLENQY DSRLDDTNRH HVIEDIRKQM DSRIHYYMSH IKKEENTPPA QYAEHIAEHV
     KRDVIRAVEH FLEHIPSEMK GDEQA
 
 
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