ID   GERPE_BACSU             Reviewed;         133 AA.
AC   O06717;
DT   26-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Probable spore germination protein GerPE;
GN   Name=gerPE; Synonyms=yisD; OrderedLocusNames=BSU10680;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9353931; DOI=10.1099/00221287-143-10-3305;
RA   Medina N., Vannier F., Roche B., Autret S., Levine A., Seror S.J.;
RT   "Sequencing of regions downstream of addA (98 degrees) and citG (289
RT   degrees) in Bacillus subtilis.";
RL   Microbiology 143:3305-3308(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   CHARACTERIZATION.
RC   STRAIN=168 / 1604;
RX   PubMed=10715007; DOI=10.1128/jb.182.7.1987-1994.2000;
RA   Behravan J., Chirakkal H., Masson A., Moir A.;
RT   "Mutations in the gerP locus of Bacillus subtilis and Bacillus cereus
RT   affect access of germinants to their targets in spores.";
RL   J. Bacteriol. 182:1987-1994(2000).
CC   -!- FUNCTION: Required for the formation of functionally normal spores.
CC       Could be involved in the establishment of normal spore coat structure
CC       and/or permeability, which allows the access of germinants to their
CC       receptor.
CC   -!- DEVELOPMENTAL STAGE: Expressed during sporulation, around the time of
CC       spore coat synthesis and assembly, in mother cell compartment.
CC   -!- INDUCTION: Expression is sigma K-dependent and negatively regulated by
CC       GerE.
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DR   EMBL; Y09476; CAA70675.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12908.1; -; Genomic_DNA.
DR   PIR; D69836; D69836.
DR   RefSeq; NP_388949.1; NC_000964.3.
DR   RefSeq; WP_010886467.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; O06717; -.
DR   STRING; 224308.BSU10680; -.
DR   PaxDb; O06717; -.
DR   PRIDE; O06717; -.
DR   DNASU; 939782; -.
DR   EnsemblBacteria; CAB12908; CAB12908; BSU_10680.
DR   GeneID; 939782; -.
DR   KEGG; bsu:BSU10680; -.
DR   PATRIC; fig|224308.179.peg.1148; -.
DR   eggNOG; ENOG503385J; Bacteria.
DR   OMA; AFCHEVP; -.
DR   BioCyc; BSUB:BSU10680-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR024496; Spore_germ_GerPE.
DR   Pfam; PF10970; GerPE; 1.
PE   1: Evidence at protein level;
KW   Germination; Reference proteome; Sporulation.
FT   CHAIN           1..133
FT                   /note="Probable spore germination protein GerPE"
FT                   /id="PRO_0000087475"
SQ   SEQUENCE   133 AA;  14814 MW;  EAB9E097F2FA202D CRC64;
     MLKRISRIRL VKFNSLGIAS VFQVGDTNEI DMSVKVFAVQ RSLSTFYHNE GSFNKKEYQI
     FQQQAVKPLP ETGVQSAFCH EVPAIYVRSI KIQGVSASSV LHAGSASLIR GDARLKHIRQ
     IQSPRSQSPA KNI