GERT_BACSU
ID GERT_BACSU Reviewed; 157 AA.
AC Q7WY67; O68259;
DT 16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Spore germination protein GerT;
GN Name=gerT; Synonyms=yozR; OrderedLocusNames=BSU19490;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9734814; DOI=10.1093/dnares/5.3.195;
RA Ghim S.-Y., Choi S.-K., Shin B.-S., Jeong Y.-M., Sorokin A., Ehrlich S.D.,
RA Park S.-H.;
RT "Sequence analysis of the Bacillus subtilis 168 chromosome region between
RT the sspC and odhA loci (184 degrees-180 degrees).";
RL DNA Res. 5:195-201(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP FUNCTION IN SPORE GERMINATION, SUBCELLULAR LOCATION, AND TRANSCRIPTION
RP REGULATION.
RX PubMed=17720779; DOI=10.1128/jb.01053-07;
RA Ferguson C.C., Camp A.H., Losick R.;
RT "gerT, a newly discovered germination gene under the control of the
RT sporulation transcription factor sigmaK in Bacillus subtilis.";
RL J. Bacteriol. 189:7681-7689(2007).
CC -!- FUNCTION: Involved in spore germination; probably required at the
CC earliest stage of germination. {ECO:0000269|PubMed:17720779}.
CC -!- SUBCELLULAR LOCATION: Spore coat {ECO:0000269|PubMed:17720779}.
CC -!- INDUCTION: Induced in late sporulation stage by sigma K. Repressed by
CC GerE.
CC -!- MISCELLANEOUS: Incorporated into the coat in two steps. First,
CC independently of CotE, assembles into foci associated with the
CC forespore. Next, in a CotE-dependent manner, spreads around the
CC developing spore to form a stable contiguous shell.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC17851.1; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF026147; AAC17851.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AL009126; CAE01457.1; -; Genomic_DNA.
DR RefSeq; WP_003231207.1; NZ_JNCM01000036.1.
DR RefSeq; YP_054583.1; NC_000964.3.
DR AlphaFoldDB; Q7WY67; -.
DR SMR; Q7WY67; -.
DR STRING; 224308.BSU19490; -.
DR PaxDb; Q7WY67; -.
DR PRIDE; Q7WY67; -.
DR EnsemblBacteria; CAE01457; CAE01457; BSU_19490.
DR GeneID; 2914248; -.
DR KEGG; bsu:BSU19490; -.
DR PATRIC; fig|224308.179.peg.2132; -.
DR eggNOG; ENOG50339SJ; Bacteria.
DR InParanoid; Q7WY67; -.
DR OMA; FEWNKYF; -.
DR BioCyc; BSUB:BSU19490-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR SUPFAM; SSF49764; SSF49764; 1.
PE 1: Evidence at protein level;
KW Germination; Reference proteome.
FT CHAIN 1..157
FT /note="Spore germination protein GerT"
FT /id="PRO_0000049675"
SQ SEQUENCE 157 AA; 18542 MW; 3606F92F0102BB61 CRC64;
MFEWNKYFPF HNQFSKEALK KADPKEVETY VNRVMESVFG SDYAAQFPFR DPLPQKEHPA
KPDAKPDVKP DIDIFETADH VFVKVPISEE WLEQVRIKHT SHELWLENLP RADHPKKVNL
PCLVKRKGTK AVYKDGLLEV MFQKQQDYNM SEVEIIR