ID   GET4_DICDI              Reviewed;         309 AA.
AC   Q54TH4;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Golgi to ER traffic protein 4 homolog;
GN   ORFNames=DDB_G0281815;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: May play a role in insertion of tail-anchored proteins into
CC       the endoplasmic reticulum membrane. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GET4 family. {ECO:0000305}.
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DR   EMBL; AAFI02000042; EAL66669.1; -; Genomic_DNA.
DR   RefSeq; XP_640617.1; XM_635525.1.
DR   AlphaFoldDB; Q54TH4; -.
DR   SMR; Q54TH4; -.
DR   STRING; 44689.DDB0266864; -.
DR   PaxDb; Q54TH4; -.
DR   EnsemblProtists; EAL66669; EAL66669; DDB_G0281815.
DR   GeneID; 8623227; -.
DR   KEGG; ddi:DDB_G0281815; -.
DR   dictyBase; DDB_G0281815; -.
DR   eggNOG; KOG3024; Eukaryota.
DR   HOGENOM; CLU_046061_1_1_1; -.
DR   InParanoid; Q54TH4; -.
DR   OMA; QIGEMYF; -.
DR   PhylomeDB; Q54TH4; -.
DR   PRO; PR:Q54TH4; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0045048; P:protein insertion into ER membrane; IBA:GO_Central.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR007317; GET4.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR12875; PTHR12875; 1.
DR   Pfam; PF04190; GET4; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..309
FT                   /note="Golgi to ER traffic protein 4 homolog"
FT                   /id="PRO_0000328387"
FT   REGION          290..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   309 AA;  35129 MW;  5BF9F060DD00404B CRC64;
     MAERVLANLE AKFTEGNYYD ILQSYKALYN RFSTQKKYKE TVTLLESGCN KFLEYKQWNC
     AADLAKLLIE CYKNFKIQYS DESKEPIIKI FKNFKGECAG KISFMRDAIE WSSKNGGDSK
     GSEEFHTLLA ITLSEEGDYI DAQKHFIFGN DYFSFCEMLK NWTEDVDEEE KDLYITRAIF
     GLLCLKKLKQ ASDLYNLFTT KVIKGDPSPL LNFDRFLLLT LERDALPLFN LLRQKYERSL
     KRDPQFKKFL DQIANIFYNV PIQSGGGLSG MLSNLLSGFG GGMGMGGNSS GGGLASMEVD
     GPTIEDEMD