ID   GET4_DROME              Reviewed;         339 AA.
AC   Q9VN19;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 131.
DE   RecName: Full=Golgi to ER traffic protein 4 homolog;
GN   ORFNames=CG9853;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- FUNCTION: May play a role in insertion of tail-anchored proteins into
CC       the endoplasmic reticulum membrane. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GET4 family. {ECO:0000305}.
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DR   EMBL; AE014297; AAF52132.1; -; Genomic_DNA.
DR   EMBL; AE014297; ABW08596.1; -; Genomic_DNA.
DR   EMBL; BT001480; AAN71235.1; -; mRNA.
DR   RefSeq; NP_001097680.1; NM_001104210.1.
DR   RefSeq; NP_001287156.1; NM_001300227.1.
DR   RefSeq; NP_649464.1; NM_141207.5.
DR   AlphaFoldDB; Q9VN19; -.
DR   SMR; Q9VN19; -.
DR   BioGRID; 65777; 2.
DR   IntAct; Q9VN19; 2.
DR   STRING; 7227.FBpp0112104; -.
DR   PaxDb; Q9VN19; -.
DR   PRIDE; Q9VN19; -.
DR   DNASU; 40557; -.
DR   EnsemblMetazoa; FBtr0078949; FBpp0078589; FBgn0086605.
DR   EnsemblMetazoa; FBtr0113192; FBpp0112104; FBgn0086605.
DR   EnsemblMetazoa; FBtr0344215; FBpp0310621; FBgn0086605.
DR   GeneID; 40557; -.
DR   KEGG; dme:Dmel_CG9853; -.
DR   UCSC; CG9853-RA; d. melanogaster.
DR   FlyBase; FBgn0086605; CG9853.
DR   VEuPathDB; VectorBase:FBgn0086605; -.
DR   eggNOG; KOG3024; Eukaryota.
DR   GeneTree; ENSGT00390000015750; -.
DR   HOGENOM; CLU_046061_2_0_1; -.
DR   InParanoid; Q9VN19; -.
DR   OMA; QIGEMYF; -.
DR   OrthoDB; 1030907at2759; -.
DR   PhylomeDB; Q9VN19; -.
DR   BioGRID-ORCS; 40557; 0 hits in 1 CRISPR screen.
DR   GenomeRNAi; 40557; -.
DR   PRO; PR:Q9VN19; -.
DR   Proteomes; UP000000803; Chromosome 3R.
DR   Bgee; FBgn0086605; Expressed in oviduct (Drosophila) and 28 other tissues.
DR   ExpressionAtlas; Q9VN19; baseline and differential.
DR   Genevisible; Q9VN19; DM.
DR   GO; GO:0071818; C:BAT3 complex; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0045048; P:protein insertion into ER membrane; IBA:GO_Central.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR007317; GET4.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR12875; PTHR12875; 1.
DR   Pfam; PF04190; GET4; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..339
FT                   /note="Golgi to ER traffic protein 4 homolog"
FT                   /id="PRO_0000328388"
SQ   SEQUENCE   339 AA;  38490 MW;  AB0A84E4D1445AFB CRC64;
     MSAAETGPIA SGSAVSTGQR GVSRVLAKLS QSLAGGEFYE AHMMYRTLYF RYTAQKRYQD
     CLELLFDGAQ QLIAKEQESS AADLCLLLVD TLEKRGPQAE DTDNFLWVPR LGALIRGLNS
     ATVERETLIQ RTIKWSTALH GQYGHPVLHK LIAHVFWTEG NIESARHHYL LCQDGSLCGR
     VLIEISQSRG FQGEMDLFLV QAVLQQLSLK DRKTAEDTFT EYTRYHAKLL KHEFPYKEPL
     VNFLYFLFRL IDAKRVAGFR ALRKLYDPSL KRDTSFLKYV AKIGVLYFDE HPEAAHSGPP
     GLGGMFGDIF NRLMAGFEED DADDHDTTLR RQNENNELE