ID   GET4_SCHPO              Reviewed;         303 AA.
AC   O74432;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Golgi to ER traffic protein 4;
GN   Name=get4; ORFNames=SPCC1672.12c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: May play a role in insertion of tail-anchored proteins into
CC       the endoplasmic reticulum membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the GET4 family. {ECO:0000305}.
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DR   EMBL; CU329672; CAA20450.1; -; Genomic_DNA.
DR   PIR; T41056; T41056.
DR   RefSeq; NP_587883.1; NM_001022875.2.
DR   AlphaFoldDB; O74432; -.
DR   SMR; O74432; -.
DR   BioGRID; 275350; 11.
DR   STRING; 4896.SPCC1672.12c.1; -.
DR   MaxQB; O74432; -.
DR   PaxDb; O74432; -.
DR   PRIDE; O74432; -.
DR   EnsemblFungi; SPCC1672.12c.1; SPCC1672.12c.1:pep; SPCC1672.12c.
DR   GeneID; 2538767; -.
DR   KEGG; spo:SPCC1672.12c; -.
DR   PomBase; SPCC1672.12c; get4.
DR   VEuPathDB; FungiDB:SPCC1672.12c; -.
DR   eggNOG; KOG3024; Eukaryota.
DR   HOGENOM; CLU_046061_0_2_1; -.
DR   InParanoid; O74432; -.
DR   OMA; QIGEMYF; -.
DR   PhylomeDB; O74432; -.
DR   PRO; PR:O74432; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0072380; C:TRC complex; ISO:PomBase.
DR   GO; GO:0045048; P:protein insertion into ER membrane; ISO:PomBase.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR007317; GET4.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR12875; PTHR12875; 1.
DR   Pfam; PF04190; GET4; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; ER-Golgi transport; Reference proteome; Transport.
FT   CHAIN           1..303
FT                   /note="Golgi to ER traffic protein 4"
FT                   /id="PRO_0000228106"
SQ   SEQUENCE   303 AA;  34352 MW;  2C664D09672138D9 CRC64;
     MDAKIKRAEG RLREDPYEGH QMLRTLVNRQ VKAKKHDDAV ALLYSGAKTL FEIEQTGSAA
     DLAIYMLDVY EKASYAASLD NKARALTLLG LFPAEEGARK QYVKRLLEWS KSAGPQGDKD
     VHFAVATMFV KWKEPASAEK HFVLGNEKSA RAYGETMYYW FTSDSSISPD TFAGRPVLNY
     LLAENLISAW NSLETFTKHF TKSNAPDVEN MSFDGKDFPV FKEYPQMNFL HLLIFTAYRK
     DKETYLSLVQ KYPKKQDWEA ALAKIEEIYF GIRPVSNQPN ILANLMSSLF SGPPAATNQL
     DLE