ID   GFCD_ECOLI              Reviewed;         698 AA.
AC   P75882;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 136.
DE   RecName: Full=Uncharacterized lipoprotein GfcD;
DE   AltName: Full=Group 4 capsule protein D homolog;
DE   Flags: Precursor;
GN   Name=gfcD; Synonyms=ymcA; OrderedLocusNames=b0984, JW0967;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- CAUTION: In E.coli K12 / MG1655 and K12 / W3110 this operon is silenced
CC       by an IS1D insertion in the promoter region. {ECO:0000305}.
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DR   EMBL; U00096; AAC74069.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA35749.1; -; Genomic_DNA.
DR   PIR; F64839; F64839.
DR   RefSeq; NP_415504.1; NC_000913.3.
DR   RefSeq; WP_000742328.1; NZ_SSZK01000002.1.
DR   AlphaFoldDB; P75882; -.
DR   BioGRID; 4261409; 175.
DR   DIP; DIP-12707N; -.
DR   IntAct; P75882; 10.
DR   STRING; 511145.b0984; -.
DR   TCDB; 1.B.14.16.11; the outer membrane receptor (omr) family.
DR   PaxDb; P75882; -.
DR   PRIDE; P75882; -.
DR   EnsemblBacteria; AAC74069; AAC74069; b0984.
DR   EnsemblBacteria; BAA35749; BAA35749; BAA35749.
DR   GeneID; 945588; -.
DR   KEGG; ecj:JW0967; -.
DR   KEGG; eco:b0984; -.
DR   PATRIC; fig|511145.12.peg.1019; -.
DR   EchoBASE; EB3493; -.
DR   eggNOG; COG4775; Bacteria.
DR   HOGENOM; CLU_007558_1_0_6; -.
DR   OMA; WARYASE; -.
DR   PhylomeDB; P75882; -.
DR   BioCyc; EcoCyc:G6505-MON; -.
DR   PRO; PR:P75882; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010344; YbjH.
DR   Pfam; PF06082; YjbH; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           19..698
FT                   /note="Uncharacterized lipoprotein GfcD"
FT                   /id="PRO_0000018057"
FT   LIPID           19
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           19
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   698 AA;  78687 MW;  37F71D2DC57FA4E7 CRC64;
     MKKNSYLLSC LAIAVSSACH AEVLTYPDPL GSSQSDFGGT GLLQMPNARI APEGEFSVNY
     RDNDQYRFYS TSVALFPWLE GTIRYTDVRT RKYSQWEDFS GDQSYKDKSF DFKLRLWEEG
     YWLPQVAFGK RDIAGTGLFD GEYLVASKQA GPFDFTLGMA WGYAGNAGNI TNPFCRVSDK
     YCHRAESHDA GDISFSDIFR GPASIFGGIE YQTPWNPLRL KLEYDGNNYQ NDFAGKLPQA
     SHFNVGAVYR AASWADLNLS YERGNTLMFG FTLRTNFNDL RPALRDTPKP AYQPAPESEG
     LQYTTVANQL TALKYNAGFD APEIQLRDKT LYMSGQQYKY RDSREAVDRA NRILVNNLPQ
     GVEKISVTQK REHMAMVTTE TDVASLRKQL AGTAPGQSEP LQQQRVEAED LSAFGRGYRI
     REDRFSYSFN PTLSQSLGGP EDFYMFQLGL MSSARYWFTD HLLLDGGIFT NIYNNYDKFK
     SSLLPADSTL PRVRTHIRDY VRNDVYLNNL QANYFADLGN GFYGQVYGGY LETMYAGVGS
     ELLYRPLDAC WALGVDVNYV KQRDWDNMMR FTDYSTPTGF VTAYWNPPTL NGVLMKLSVG
     QYLAKDKGAT IDVAKRFDSG VAVGVWAAIS NVSKDDYGEG GFSKGFYISI PFDLMTIGPN
     RNRAVVSWTP LTRDGGQMLS RKYQLYPMTA EREVPVGQ