ID   GFCE_ECO57              Reviewed;         379 AA.
AC   P0A933; P75881;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Putative polysaccharide export protein GfcE;
DE   AltName: Full=Group 4 capsule protein E homolog;
DE   Flags: Precursor;
GN   Name=gfcE; OrderedLocusNames=Z1400, ECs1139;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: May be involved in polysaccharide transport. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BexD/CtrA/VexA family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG55531.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34562.1; -; Genomic_DNA.
DR   PIR; C90771; C90771.
DR   PIR; G85633; G85633.
DR   RefSeq; NP_309166.1; NC_002695.1.
DR   RefSeq; WP_001295357.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0A933; -.
DR   SMR; P0A933; -.
DR   STRING; 155864.EDL933_1321; -.
DR   EnsemblBacteria; AAG55531; AAG55531; Z1400.
DR   EnsemblBacteria; BAB34562; BAB34562; ECs_1139.
DR   GeneID; 915179; -.
DR   KEGG; ece:Z1400; -.
DR   KEGG; ecs:ECs_1139; -.
DR   PATRIC; fig|386585.9.peg.1255; -.
DR   eggNOG; COG1596; Bacteria.
DR   HOGENOM; CLU_038343_4_2_6; -.
DR   OMA; LQFPYAG; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015159; F:polysaccharide transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003715; Poly_export.
DR   InterPro; IPR019554; Soluble_ligand-bd.
DR   InterPro; IPR040716; Wza_C.
DR   Pfam; PF02563; Poly_export; 1.
DR   Pfam; PF10531; SLBB; 2.
DR   Pfam; PF18412; Wza_C; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Lipoprotein; Membrane; Palmitate;
KW   Polysaccharide transport; Porin; Reference proteome; Signal;
KW   Sugar transport; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           21..379
FT                   /note="Putative polysaccharide export protein GfcE"
FT                   /id="PRO_0000025227"
FT   LIPID           21
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           21
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   379 AA;  41741 MW;  36A5F5B9E9C5E842 CRC64;
     MKKNIFKFSV LTLAVLSLTA CTLVPGQNLS TSNKDVIELP DNQYDLDKMV NIYPVTPGLI
     DQLRAKPIMS QANPELEQQI ANYEYRIGIG DVLMVTVWDH PELTTPAGQY RSASDTGNWV
     NADGAIFYPY IGRLKVAGKT LTQVRNEITA RLDSVIESPQ VDVSVAAFRS QKAYVTGEVS
     KSGQQPITNI PLTIMDAINA AGGLTADADW RNVVLTQNGV KTKVNLYALM QRGDLRQNKL
     LHPGDILFIP RNDDLKVFVM GEVGKQSTLK MDRSGMTLAE ALGNAEGMNQ DVADATGIFV
     IRATQNKQNG KIANIYQLNA KDASAMILGT EFQLEPYDIV YVTTAPLARW NRVISLLVPT
     ISGVHDLTET SRWIQTWPN