GFCE_ECOLI
ID GFCE_ECOLI Reviewed; 379 AA.
AC P0A932; P75881;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Putative polysaccharide export protein GfcE;
DE AltName: Full=Group 4 capsule protein E homolog;
DE Flags: Precursor;
GN Name=gfcE; Synonyms=yccZ; OrderedLocusNames=b0983, JW0966;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: May be involved in polysaccharide transport.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BexD/CtrA/VexA family. {ECO:0000305}.
CC -!- CAUTION: In E.coli K12 / MG1655 and K12 / W3110 this operon is silenced
CC by an IS1D insertion in the promoter region. {ECO:0000305}.
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DR EMBL; U00096; AAC74068.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35748.1; -; Genomic_DNA.
DR PIR; E64839; E64839.
DR RefSeq; NP_415503.1; NC_000913.3.
DR RefSeq; WP_001295357.1; NZ_STEB01000006.1.
DR AlphaFoldDB; P0A932; -.
DR SMR; P0A932; -.
DR BioGRID; 4261408; 168.
DR STRING; 511145.b0983; -.
DR TCDB; 1.B.18.3.8; the outer membrane auxiliary (oma) protein family.
DR PaxDb; P0A932; -.
DR PRIDE; P0A932; -.
DR EnsemblBacteria; AAC74068; AAC74068; b0983.
DR EnsemblBacteria; BAA35748; BAA35748; BAA35748.
DR GeneID; 945586; -.
DR KEGG; ecj:JW0966; -.
DR KEGG; eco:b0983; -.
DR PATRIC; fig|1411691.4.peg.1290; -.
DR EchoBASE; EB3492; -.
DR eggNOG; COG1596; Bacteria.
DR HOGENOM; CLU_038343_4_2_6; -.
DR InParanoid; P0A932; -.
DR OMA; RYEYKVG; -.
DR PhylomeDB; P0A932; -.
DR BioCyc; EcoCyc:G6504-MON; -.
DR PRO; PR:P0A932; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0015159; F:polysaccharide transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR003715; Poly_export.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR040716; Wza_C.
DR Pfam; PF02563; Poly_export; 1.
DR Pfam; PF10531; SLBB; 2.
DR Pfam; PF18412; Wza_C; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Ion transport; Lipoprotein; Membrane; Palmitate;
KW Polysaccharide transport; Porin; Reference proteome; Signal;
KW Sugar transport; Transmembrane; Transmembrane beta strand; Transport.
FT SIGNAL 1..20
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 21..379
FT /note="Putative polysaccharide export protein GfcE"
FT /id="PRO_0000025226"
FT LIPID 21
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 21
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ SEQUENCE 379 AA; 41741 MW; 36A5F5B9E9C5E842 CRC64;
MKKNIFKFSV LTLAVLSLTA CTLVPGQNLS TSNKDVIELP DNQYDLDKMV NIYPVTPGLI
DQLRAKPIMS QANPELEQQI ANYEYRIGIG DVLMVTVWDH PELTTPAGQY RSASDTGNWV
NADGAIFYPY IGRLKVAGKT LTQVRNEITA RLDSVIESPQ VDVSVAAFRS QKAYVTGEVS
KSGQQPITNI PLTIMDAINA AGGLTADADW RNVVLTQNGV KTKVNLYALM QRGDLRQNKL
LHPGDILFIP RNDDLKVFVM GEVGKQSTLK MDRSGMTLAE ALGNAEGMNQ DVADATGIFV
IRATQNKQNG KIANIYQLNA KDASAMILGT EFQLEPYDIV YVTTAPLARW NRVISLLVPT
ISGVHDLTET SRWIQTWPN
