ID   GFCE_SHIFL              Reviewed;         379 AA.
AC   P0A934; P75881;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Putative polysaccharide export protein GfcE;
DE   AltName: Full=Group 4 capsule protein E homolog;
DE   Flags: Precursor;
GN   Name=gfcE; OrderedLocusNames=SF0985, S1052;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: May be involved in polysaccharide transport. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BexD/CtrA/VexA family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE005674; AAN42613.2; -; Genomic_DNA.
DR   EMBL; AE014073; AAP16497.1; -; Genomic_DNA.
DR   RefSeq; NP_706906.2; NC_004337.2.
DR   RefSeq; WP_001295357.1; NZ_WPGW01000043.1.
DR   AlphaFoldDB; P0A934; -.
DR   SMR; P0A934; -.
DR   STRING; 198214.SF0985; -.
DR   EnsemblBacteria; AAN42613; AAN42613; SF0985.
DR   EnsemblBacteria; AAP16497; AAP16497; S1052.
DR   GeneID; 1023946; -.
DR   KEGG; sfl:SF0985; -.
DR   KEGG; sfx:S1052; -.
DR   PATRIC; fig|198214.7.peg.1146; -.
DR   HOGENOM; CLU_038343_4_2_6; -.
DR   OrthoDB; 687725at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015159; F:polysaccharide transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003715; Poly_export.
DR   InterPro; IPR019554; Soluble_ligand-bd.
DR   InterPro; IPR040716; Wza_C.
DR   Pfam; PF02563; Poly_export; 1.
DR   Pfam; PF10531; SLBB; 2.
DR   Pfam; PF18412; Wza_C; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Lipoprotein; Membrane; Palmitate;
KW   Polysaccharide transport; Porin; Reference proteome; Signal;
KW   Sugar transport; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           21..379
FT                   /note="Putative polysaccharide export protein GfcE"
FT                   /id="PRO_0000025228"
FT   LIPID           21
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           21
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   379 AA;  41741 MW;  36A5F5B9E9C5E842 CRC64;
     MKKNIFKFSV LTLAVLSLTA CTLVPGQNLS TSNKDVIELP DNQYDLDKMV NIYPVTPGLI
     DQLRAKPIMS QANPELEQQI ANYEYRIGIG DVLMVTVWDH PELTTPAGQY RSASDTGNWV
     NADGAIFYPY IGRLKVAGKT LTQVRNEITA RLDSVIESPQ VDVSVAAFRS QKAYVTGEVS
     KSGQQPITNI PLTIMDAINA AGGLTADADW RNVVLTQNGV KTKVNLYALM QRGDLRQNKL
     LHPGDILFIP RNDDLKVFVM GEVGKQSTLK MDRSGMTLAE ALGNAEGMNQ DVADATGIFV
     IRATQNKQNG KIANIYQLNA KDASAMILGT EFQLEPYDIV YVTTAPLARW NRVISLLVPT
     ISGVHDLTET SRWIQTWPN