ID   GFOD1_XENTR             Reviewed;         390 AA.
AC   Q6P4M5;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Glucose-fructose oxidoreductase domain-containing protein 1;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=gfod1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family. {ECO:0000305}.
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DR   EMBL; BC063342; AAH63342.1; -; mRNA.
DR   RefSeq; NP_989170.1; NM_203839.1.
DR   AlphaFoldDB; Q6P4M5; -.
DR   SMR; Q6P4M5; -.
DR   STRING; 8364.ENSXETP00000054189; -.
DR   PaxDb; Q6P4M5; -.
DR   DNASU; 394777; -.
DR   Ensembl; ENSXETT00000054189; ENSXETP00000054189; ENSXETG00000025401.
DR   GeneID; 394777; -.
DR   KEGG; xtr:394777; -.
DR   CTD; 54438; -.
DR   Xenbase; XB-GENE-947602; gfod1.
DR   eggNOG; KOG2742; Eukaryota.
DR   HOGENOM; CLU_023194_8_0_1; -.
DR   InParanoid; Q6P4M5; -.
DR   OMA; NDRRNWN; -.
DR   OrthoDB; 673027at2759; -.
DR   TreeFam; TF323246; -.
DR   Reactome; R-XTR-9013406; RHOQ GTPase cycle.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000025401; Expressed in brain and 13 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Oxidoreductase; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..390
FT                   /note="Glucose-fructose oxidoreductase domain-containing
FT                   protein 1"
FT                   /id="PRO_0000282970"
FT   CARBOHYD        161
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        270
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        354
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   390 AA;  43352 MW;  C15996CD31AEF859 CRC64;
     MLPGVGVFGT SLTSRVIIPL LKDEGFSVKA LWGRTQEEAE ELAKEMSVPF YTNRIDDVLL
     HQDVDLVCIN LPPPLTKQIA VKTLGIGKNV ICDRTATPLD AFRMMSAAHY YPKLMSIMGN
     VLRFLPAFVK MKQLIQEGYV GELQVCEVQV HSGSLLGKKY NWSCDDLMGG GGLHSVGSYI
     IDLLTFLTSQ KAVKVHGLLK TFVKQTDHIK GIRQITSDDF CTFQMVLEGG VCCTVTLNFN
     VPGEFKQDVI VVGSAGRLIV TGIDLYGQRN SSSDRELLLK DSTPVSNSLL PEKAFSDIPS
     PYLRGTIKMV QAVRQAFQDQ DDRRTWDGRP LTMAATFDDC LYALCVVDTI KKSNQTGEWQ
     NIVIMTEEPE LSPAYLISEA MRRSRMSLYC