ID   GFOD2_XENLA             Reviewed;         384 AA.
AC   Q7ZY75;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Glucose-fructose oxidoreductase domain-containing protein 2;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=gfod2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Larva;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Promotes matrix assembly. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family. {ECO:0000305}.
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DR   EMBL; BC043911; AAH43911.1; -; mRNA.
DR   EMBL; BC084383; AAH84383.1; -; mRNA.
DR   RefSeq; NP_001079508.1; NM_001086039.2.
DR   RefSeq; XP_018111913.1; XM_018256424.1.
DR   RefSeq; XP_018111914.1; XM_018256425.1.
DR   AlphaFoldDB; Q7ZY75; -.
DR   SMR; Q7ZY75; -.
DR   DNASU; 379195; -.
DR   GeneID; 379195; -.
DR   KEGG; xla:379195; -.
DR   CTD; 379195; -.
DR   Xenbase; XB-GENE-5740241; gfod2.L.
DR   OMA; EMPLPHL; -.
DR   OrthoDB; 673027at2759; -.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 379195; Expressed in oocyte and 19 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   2: Evidence at transcript level;
KW   Extracellular matrix; Oxidoreductase; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..384
FT                   /note="Glucose-fructose oxidoreductase domain-containing
FT                   protein 2"
FT                   /id="PRO_0000282974"
FT   REGION          358..384
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        367..384
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   384 AA;  42546 MW;  2BFB503229CFDACB CRC64;
     MMTLPGIGVF GTGNTARVLI QLLRAEGFSI EALWGKTDED AKVVAEEMGI PFYTSHTDDV
     LLHQEVDLVC ISIPPPLTRQ IAVKALGIGK NVICEKAASS LDAFTMVKAA RYYPKLMSLV
     GNALRFLPAF DRMRQLILEQ GYVGEIRICD VRVYGGSLLS SNYSWICDDL MGGGGLHTLG
     TYLVDLLTHL TNKKAEKVHG FLKTFVKQNE AISGIRYVTS DDFCFFQMQM TGGACSTVTL
     NFNMPGTFVH EVMVVGSAGR LVVRGTELYG QKNSASEEKL LLSEPLTSDI ADVSDFDKVP
     PPYLMGIAHM VKALRQSFQD QEDRRTWDHK PLSVAATFED GLYMQRVVDA IKRSNRSGEW
     ESVELTNEET DSNQNLSEVI QHNL