ID   GFOD2_XENTR             Reviewed;         384 AA.
AC   Q5BKK6;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Glucose-fructose oxidoreductase domain-containing protein 2;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=gfod2;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Promotes matrix assembly. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family. {ECO:0000305}.
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DR   EMBL; BC091040; AAH91040.1; -; mRNA.
DR   RefSeq; NP_001025591.1; NM_001030420.1.
DR   RefSeq; XP_012816668.1; XM_012961214.2.
DR   RefSeq; XP_012816669.1; XM_012961215.2.
DR   RefSeq; XP_012816670.1; XM_012961216.2.
DR   AlphaFoldDB; Q5BKK6; -.
DR   SMR; Q5BKK6; -.
DR   PaxDb; Q5BKK6; -.
DR   Ensembl; ENSXETT00000034069; ENSXETP00000034069; ENSXETG00000015621.
DR   GeneID; 594979; -.
DR   KEGG; xtr:594979; -.
DR   CTD; 81577; -.
DR   Xenbase; XB-GENE-5740207; gfod2.
DR   eggNOG; KOG2742; Eukaryota.
DR   HOGENOM; CLU_023194_8_0_1; -.
DR   InParanoid; Q5BKK6; -.
DR   OMA; EMPLPHL; -.
DR   OrthoDB; 673027at2759; -.
DR   PhylomeDB; Q5BKK6; -.
DR   TreeFam; TF323246; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000015621; Expressed in egg cell and 12 other tissues.
DR   GO; GO:0031012; C:extracellular matrix; IBA:GO_Central.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; IBA:GO_Central.
DR   InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   2: Evidence at transcript level;
KW   Extracellular matrix; Oxidoreductase; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..384
FT                   /note="Glucose-fructose oxidoreductase domain-containing
FT                   protein 2"
FT                   /id="PRO_0000282975"
FT   REGION          358..384
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        367..384
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   384 AA;  42705 MW;  4AA7824C0CD7B488 CRC64;
     MKTLPGIGVF GTGNTARVLI SLLRADGFSI EALWGKTDEE AKELAEEMGI PFYTCHTDDV
     LLHQEVDLVC ISIPPPLTRQ IAVKALGIGK NVICEKAASS IDAFTMVKAA RYYPKLMSLV
     GNALRFLPAF DRMRQLILEQ NYVGEIRICD VRVYGGSLLS SNYSWICDDL MGGGGLHTLG
     TYLVDLLTHL TNKRAEKVHG FLKTFVKQNE AISGIRYVTS DDFCFFQMQM TGGACSTVTL
     NFNMPGTFVH EVMVVGSAGR LVVRGTELFG QKNSASEEKL LLSDPLTREI ADISDFEKVP
     PPYLMGIAHM VKALRQSFQD QEDRRTWDQK PLSVAATFED GLYMQRVVDA IKRSNRSGEW
     ESVELTNDET DSNQNLSEVI QHNL