GG6L4_HUMAN
ID GG6L4_HUMAN Reviewed; 574 AA.
AC A6NEF3; D6REZ9;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2013, sequence version 3.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Golgin subfamily A member 6-like protein 4;
GN Name=GOLGA6L4;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16572171; DOI=10.1038/nature04601;
RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT "Analysis of the DNA sequence and duplication history of human chromosome
RT 15.";
RL Nature 440:671-675(2006).
CC -!- SIMILARITY: Belongs to the GOLGA6 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC136698; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS73774.1; -.
DR RefSeq; NP_001254465.2; NM_001267536.2.
DR AlphaFoldDB; A6NEF3; -.
DR SMR; A6NEF3; -.
DR iPTMnet; A6NEF3; -.
DR PhosphoSitePlus; A6NEF3; -.
DR BioMuta; GOLGA6L4; -.
DR MassIVE; A6NEF3; -.
DR PaxDb; A6NEF3; -.
DR PeptideAtlas; A6NEF3; -.
DR PRIDE; A6NEF3; -.
DR Antibodypedia; 65891; 16 antibodies from 6 providers.
DR DNASU; 643707; -.
DR Ensembl; ENST00000510439.7; ENSP00000421586.2; ENSG00000184206.13.
DR GeneID; 643707; -.
DR KEGG; hsa:643707; -.
DR MANE-Select; ENST00000510439.7; ENSP00000421586.2; NM_001267536.3; NP_001254465.2.
DR UCSC; uc059mrg.1; human.
DR CTD; 643707; -.
DR GeneCards; GOLGA6L4; -.
DR HGNC; HGNC:27256; GOLGA6L4.
DR HPA; ENSG00000184206; Low tissue specificity.
DR neXtProt; NX_A6NEF3; -.
DR VEuPathDB; HostDB:ENSG00000184206; -.
DR eggNOG; KOG4725; Eukaryota.
DR GeneTree; ENSGT00910000144587; -.
DR InParanoid; A6NEF3; -.
DR OMA; KNIAGAN; -.
DR OrthoDB; 414384at7742; -.
DR PhylomeDB; A6NEF3; -.
DR PathwayCommons; A6NEF3; -.
DR BioGRID-ORCS; 643707; 51 hits in 225 CRISPR screens.
DR GenomeRNAi; 643707; -.
DR Pharos; A6NEF3; Tdark.
DR PRO; PR:A6NEF3; -.
DR Proteomes; UP000005640; Chromosome 15.
DR RNAct; A6NEF3; protein.
DR Bgee; ENSG00000184206; Expressed in left ovary and 96 other tissues.
DR ExpressionAtlas; A6NEF3; baseline and differential.
DR Genevisible; A6NEF3; HS.
DR InterPro; IPR026737; GOLGA6L.
DR InterPro; IPR043976; GOLGA_cons_dom.
DR PANTHER; PTHR23143; PTHR23143; 3.
DR Pfam; PF15070; GOLGA2L5; 1.
PE 3: Inferred from homology;
KW Coiled coil; Reference proteome.
FT CHAIN 1..574
FT /note="Golgin subfamily A member 6-like protein 4"
FT /id="PRO_0000332264"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 157..496
FT /evidence="ECO:0000255"
FT COMPBIAS 50..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 574 AA; 67563 MW; 1B501FFBE38A1020 CRC64;
MWPQPRFPPH PAMSEKTQQG KLAAAKKKLK AYWQRKSPGI PAGANRKKKI NGSSPDTATS
GGYHSPGDSA TGIYGEGRAS STTLEDLESQ YQELAVALDS SSAIISQLTE NINSLVRTSK
EEKKHEIHLV QKLGRSLFKL KNQTAEPLAP EPPAGPSKVE QLQDETNHLR KELESVGRQL
QAEVENNQML SLLNRRQEER LREQEERLRE QEERLREQED RLHEQEERLR EQEERLCEQE
ERLREHEERL CEQEERLCEQ EERLREQEER LHEQEERLRE QEERLCEQEE RLREQEERLC
EQEERLREQE ERLCEQEKLP GQERLLEEVE KLLEQERRQE EQERLLERER LLEEVEKLLE
QERQQEEQER LLERERLLEE VEKLLEQERR QEEQERLLER ERLLDEVEEL LDEVEELLEQ
ERLRQQDERL WQQETLQELE RLRELERLRE LERMLELGWE ALYEQRAEPR SGFEELNNEN
KSTLQLEQQV KELKKSGGAE EPRGSESAAA ARPVAGAPVP QGAWMCGQAG WTPQEHPGLS
GEAVGTGEAA GGAGEAACHS FRAAENRELN ITII