ID   GG6L6_HUMAN             Reviewed;         724 AA.
AC   A8MZA4; D3YTC0;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-JAN-2016, sequence version 4.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Golgin subfamily A member 6-like protein 6;
GN   Name=GOLGA6L6;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA   Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA   Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
CC   -!- SIMILARITY: Belongs to the GOLGA6 family. {ECO:0000305}.
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DR   EMBL; AC023310; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS45184.1; -.
DR   RefSeq; NP_001138476.2; NM_001145004.2.
DR   AlphaFoldDB; A8MZA4; -.
DR   SMR; A8MZA4; -.
DR   STRING; 9606.ENSP00000480376; -.
DR   iPTMnet; A8MZA4; -.
DR   PhosphoSitePlus; A8MZA4; -.
DR   BioMuta; GOLGA6L6; -.
DR   EPD; A8MZA4; -.
DR   MassIVE; A8MZA4; -.
DR   PaxDb; A8MZA4; -.
DR   PeptideAtlas; A8MZA4; -.
DR   PRIDE; A8MZA4; -.
DR   ProteomicsDB; 2465; -.
DR   Antibodypedia; 78143; 2 antibodies from 2 providers.
DR   Ensembl; ENST00000619213.1; ENSP00000480376.1; ENSG00000277322.1.
DR   GeneID; 727832; -.
DR   KEGG; hsa:727832; -.
DR   MANE-Select; ENST00000619213.1; ENSP00000480376.1; NM_001145004.2; NP_001138476.2.
DR   CTD; 727832; -.
DR   GeneCards; GOLGA6L6; -.
DR   HGNC; HGNC:37225; GOLGA6L6.
DR   HPA; ENSG00000277322; Tissue enriched (testis).
DR   neXtProt; NX_A8MZA4; -.
DR   OpenTargets; ENSG00000277322; -.
DR   VEuPathDB; HostDB:ENSG00000277322; -.
DR   eggNOG; KOG4725; Eukaryota.
DR   GeneTree; ENSGT00940000163338; -.
DR   InParanoid; A8MZA4; -.
DR   OMA; KQHTHER; -.
DR   OrthoDB; 358120at2759; -.
DR   TreeFam; TF316990; -.
DR   PathwayCommons; A8MZA4; -.
DR   BioGRID-ORCS; 727832; 148 hits in 610 CRISPR screens.
DR   GenomeRNAi; 727832; -.
DR   Pharos; A8MZA4; Tdark.
DR   PRO; PR:A8MZA4; -.
DR   Proteomes; UP000005640; Chromosome 15.
DR   RNAct; A8MZA4; protein.
DR   Bgee; ENSG00000277322; Expressed in left testis and 3 other tissues.
DR   InterPro; IPR026737; GOLGA6L.
DR   PANTHER; PTHR23143; PTHR23143; 5.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..724
FT                   /note="Golgin subfamily A member 6-like protein 6"
FT                   /id="PRO_0000332267"
FT   REGION          1..108
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          314..342
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          374..454
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          517..548
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          561..724
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          164..686
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        9..32
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        43..57
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..95
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   724 AA;  90952 MW;  88688B5499BA2745 CRC64;
     MLMWPQPHLP THPHLPTHPH LPTHPHLPTH PHLPTHPMMS KETRQSKLAE AKEQLTDHHP
     QTNPSVGTAA SDTKKKKINN GTNPETTTSG GCHSPEDEQK ASHQHQEALR RELEAQVHTI
     RILTCQKTEL QMALYYSQHA VKQLEGEARD LISRLHDSWK FAGELEQALS AVATQKKKAD
     RYIEELTKER DALSLELYRN TITDEELKEK NAELQEKLQL VESEKSEIQL NVKELKRKLE
     RAKLLLPQQQ LQAEADHLGK ELQSVSAKLQ AQVEENELWN RLNQQQEEKM WRQEEKIQEW
     EEKIQEQEEK IREQEEKIRE QEEKMRRQEE MMWEKEEKMR RQEEMMWEKE EKMRRQEEMM
     WEKEEKIREL EEKMHEQEKI REQEEKRQEE EKIREQEKRQ EQEAKMWRQE EKIREQEEKI
     REQEKKMWRQ EEKIHEQEKI REEEKRQEQE EMWRQEEKIR EQEEIWRQKE KMHEQEEKIR
     KQEEKVWRQE EKIREQEEKI REQEEKMWRQ EEKIREQEEM WREEEKMHEQ EKIWEEEKRQ
     EQEDKMWRQE EKIREQEEKV WRQEEKIREQ EEKRQEQEEK MWKQEEKIRE QEEKIREQEE
     KIREQEEKIR EQEEMTQEQE EKMGEQEEKM CEQEEKMQEQ EETMWRQEEK IREQEKKIRE
     QEEKIREQEE MMQEQEEKMW EQEEKMCEQE EKMQEQEEKM RRQEEKMWEQ EVRLRQQEEK
     MQEH