GG6LV_HUMAN
ID GG6LV_HUMAN Reviewed; 810 AA.
AC H0YM25; A0A087X0V3;
DT 11-JUN-2014, integrated into UniProtKB/Swiss-Prot.
DT 28-MAR-2018, sequence version 2.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Golgin subfamily A member 6-like protein 22 {ECO:0000305};
GN Name=GOLGA6L22 {ECO:0000312|HGNC:HGNC:50289};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16572171; DOI=10.1038/nature04601;
RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT "Analysis of the DNA sequence and duplication history of human chromosome
RT 15.";
RL Nature 440:671-675(2006).
CC -!- SIMILARITY: Belongs to the GOLGA6 family. {ECO:0000305}.
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DR EMBL; AC100757; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0YM25; -.
DR SMR; H0YM25; -.
DR PhosphoSitePlus; H0YM25; -.
DR BioMuta; GOLGA6L22; -.
DR EPD; H0YM25; -.
DR MassIVE; H0YM25; -.
DR PaxDb; H0YM25; -.
DR PeptideAtlas; H0YM25; -.
DR PRIDE; H0YM25; -.
DR Ensembl; ENST00000622895.1; ENSP00000483673.1; ENSG00000277865.5.
DR MANE-Select; ENST00000622895.2; ENSP00000483673.2; NM_001396956.1; NP_001383885.1.
DR GeneCards; GOLGA6L22; -.
DR HGNC; HGNC:50289; GOLGA6L22.
DR HPA; ENSG00000277865; Tissue enriched (testis).
DR neXtProt; NX_H0YM25; -.
DR OpenTargets; ENSG00000277865; -.
DR VEuPathDB; HostDB:ENSG00000277865; -.
DR eggNOG; KOG4725; Eukaryota.
DR GeneTree; ENSGT00940000163338; -.
DR InParanoid; H0YM25; -.
DR OMA; NIHREPV; -.
DR TreeFam; TF316990; -.
DR Pharos; H0YM25; Tdark.
DR PRO; PR:H0YM25; -.
DR Proteomes; UP000005640; Chromosome 15.
DR RNAct; H0YM25; protein.
DR Bgee; ENSG00000277865; Expressed in right testis and 10 other tissues.
DR ExpressionAtlas; H0YM25; baseline and differential.
DR InterPro; IPR026737; GOLGA6L.
DR PANTHER; PTHR23143; PTHR23143; 6.
PE 3: Inferred from homology;
KW Coiled coil; Reference proteome.
FT CHAIN 1..810
FT /note="Golgin subfamily A member 6-like protein 22"
FT /id="PRO_0000429275"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 60..810
FT /evidence="ECO:0000255"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 810 AA; 102665 MW; B734C97AF83891A7 CRC64;
MMSKETRQSK LAEAKEQLTD HHPQTNPSVG TAASDTKKKK INNGTSPETT TSGGCHSPED
EQKASHQHQE ALRRELEAQV HTIRILTCQK TELQMALYYS QHAVKQLEGE ARDLISRLHD
SWKFAGELEQ ALSAVTTQKK KADRYIEELT KERDALSLEL YRNTITDEEL KEKNAKLQEK
LQLVESEKSE IQLNVKELKR KLERAKLLLP QQLQAEADHL GKELQSVSAK LQAQVEENEL
WNRLNQQQEE KMWRQEEKIQ EWEEKIQEQE EKIREQEEKI REQEEKMRRQ EEMMWEKEEK
MRRQEEMMWE KEEKIRELEE KMHEQEKIRE QEEKRQEEEK IREQEKRQEQ EAKMWRQEEK
IREQEEKIRE QEKKMWRQEE KIHEQEKIRE EEKRQEQEEM WRQEEKIREQ EEIWRQKEKM
HEQEEKIRKQ EEKVWRQEEK MHDQEEKIRE QEEKVWRQEE KIREQEKKRE QEEKMWRQEE
KIREQEEKIR EQEEMWREEE KMHEQEKIWE EEKRQEQEDK MWRQEEKIRE QEEKVWRQEE
KIREQEEKRQ EQEEKMWKQE EKIREQEEKI REQEEKIREQ EEKIREQEEM MQEQEEKMGE
QEEKMQEQEK MRRQEEKIRE QEEKIREQKE KIREQEEKIW EQEEKIREQE EMMQEQEEKM
GEQEEKIWEQ EEKMQEQEEK MRRQEEKIRE QEKKIREQEE KIREQEEMMQ EQEEKMGEQE
EKMQEQEEKM RRQEEKIREQ EKKIREQEEK IREQEEMMQE QEEKMWEQEE KMCEQEEKMQ
EQEEKMRRQE EKMWEQEVRL RQQEEKMQEH