GGEE3_HUMAN
ID GGEE3_HUMAN Reviewed; 111 AA.
AC Q5JRK9; A1L414;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Putative G antigen family E member 3;
DE AltName: Full=Prostate-associated gene 2B protein;
DE Short=PAGE-2B;
GN Name=PAGE2B; Synonyms=GAGEE3;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15772651; DOI=10.1038/nature03440;
RA Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA Rogers J., Bentley D.R.;
RT "The DNA sequence of the human X chromosome.";
RL Nature 434:325-337(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the GAGE family. {ECO:0000305}.
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DR EMBL; AL590240; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC130359; AAI30360.1; -; mRNA.
DR CCDS; CCDS35304.1; -.
DR RefSeq; NP_001015038.1; NM_001015038.2.
DR RefSeq; XP_011507295.1; XM_011508993.2.
DR RefSeq; XP_011529089.1; XM_011530787.2.
DR RefSeq; XP_016855447.1; XM_016999958.1.
DR RefSeq; XP_016855448.1; XM_016999959.1.
DR RefSeq; XP_016885002.1; XM_017029513.1.
DR AlphaFoldDB; Q5JRK9; -.
DR SMR; Q5JRK9; -.
DR BioGRID; 133305; 7.
DR STRING; 9606.ENSP00000364110; -.
DR iPTMnet; Q5JRK9; -.
DR PhosphoSitePlus; Q5JRK9; -.
DR BioMuta; PAGE2B; -.
DR DMDM; 74741864; -.
DR EPD; Q5JRK9; -.
DR MassIVE; Q5JRK9; -.
DR MaxQB; Q5JRK9; -.
DR PaxDb; Q5JRK9; -.
DR PeptideAtlas; Q5JRK9; -.
DR PRIDE; Q5JRK9; -.
DR ProteomicsDB; 63097; -.
DR Antibodypedia; 71518; 33 antibodies from 9 providers.
DR DNASU; 389860; -.
DR Ensembl; ENST00000374971.2; ENSP00000364110.1; ENSG00000238269.9.
DR GeneID; 389860; -.
DR KEGG; hsa:389860; -.
DR MANE-Select; ENST00000374971.2; ENSP00000364110.1; NM_001015038.3; NP_001015038.1.
DR UCSC; uc004due.5; human.
DR CTD; 389860; -.
DR GeneCards; PAGE2B; -.
DR HGNC; HGNC:31805; PAGE2B.
DR HPA; ENSG00000238269; Tissue enriched (testis).
DR MalaCards; PAGE2B; -.
DR neXtProt; NX_Q5JRK9; -.
DR OpenTargets; ENSG00000238269; -.
DR PharmGKB; PA142671203; -.
DR VEuPathDB; HostDB:ENSG00000238269; -.
DR eggNOG; ENOG502TF3A; Eukaryota.
DR GeneTree; ENSGT00940000153097; -.
DR InParanoid; Q5JRK9; -.
DR OMA; TFDPTKM; -.
DR OrthoDB; 1551004at2759; -.
DR PhylomeDB; Q5JRK9; -.
DR TreeFam; TF340669; -.
DR PathwayCommons; Q5JRK9; -.
DR BioGRID-ORCS; 389860; 8 hits in 612 CRISPR screens.
DR ChiTaRS; PAGE2B; human.
DR GenomeRNAi; 389860; -.
DR Pharos; Q5JRK9; Tdark.
DR PRO; PR:Q5JRK9; -.
DR Proteomes; UP000005640; Chromosome X.
DR RNAct; Q5JRK9; protein.
DR Bgee; ENSG00000238269; Expressed in right testis and 87 other tissues.
DR ExpressionAtlas; Q5JRK9; baseline and differential.
DR Genevisible; Q5JRK9; HS.
DR InterPro; IPR031320; GAGE.
DR InterPro; IPR008625; GAGE_fam.
DR PANTHER; PTHR14047; PTHR14047; 1.
DR Pfam; PF05831; GAGE; 1.
DR SMART; SM01379; GAGE; 1.
PE 3: Inferred from homology;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..111
FT /note="Putative G antigen family E member 3"
FT /id="PRO_0000247363"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 97
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q96GU1"
SQ SEQUENCE 111 AA; 12041 MW; FEC19407449FCDD0 CRC64;
MSEHVRTRSQ SSERGNDQES SQPVGSVIVQ EPTEEKRQEE EPPTDNQGIA PSGEIENEGA
PAVQGPDMEA FQQELALLKI EDEPGDGPDV REGIMPTFDL TKVLEAGDAQ P
