ID   GHL3_MONBE              Reviewed;        1191 AA.
AC   A9US33;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Putative glycoside hydrolase 22789;
DE            EC=3.2.1.-;
GN   ORFNames=22789;
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154;
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
RN   [2]
RP   PUTATIVE FUNCTION, AND FAMILY ASSIGNMENT.
RX   PubMed=20556855; DOI=10.1142/s0219720010004628;
RA   Naumoff D.G.;
RT   "GH101 family of glycoside hydrolases: subfamily structure and evolutionary
RT   connections with other families.";
RL   J. Bioinform. Comput. Biol. 8:437-451(2010).
CC   -!- SIMILARITY: Belongs to the glycoside hydrolase-like 3 (GHL3) family.
CC       {ECO:0000305}.
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DR   EMBL; CH991544; EDQ92033.1; -; Genomic_DNA.
DR   RefSeq; XP_001743319.1; XM_001743267.1.
DR   AlphaFoldDB; A9US33; -.
DR   EnsemblProtists; EDQ92033; EDQ92033; MONBRDRAFT_22789.
DR   GeneID; 5888464; -.
DR   KEGG; mbr:MONBRDRAFT_22789; -.
DR   eggNOG; ENOG502SHKS; Eukaryota.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR046226; DUF6259.
DR   Pfam; PF19773; DUF6259; 1.
PE   3: Inferred from homology;
KW   Glycosidase; Hydrolase; Reference proteome.
FT   CHAIN           1..1191
FT                   /note="Putative glycoside hydrolase 22789"
FT                   /id="PRO_0000408873"
FT   REGION          173..221
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        173..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1191 AA;  129012 MW;  DF6215087F6259A9 CRC64;
     MDPNNAAASS AHDLSSLDLS CLNEAERIVI NSFMRGPHAH FEHLGVGPNV KWDENLSKRA
     FYHLVAINHA TLKLLVAQAR LCSMQQMNAP NLTNGASATA LGSLHPFSLG NPATSVTMAS
     NPLANGPGLR TQLMAPDFAL ALLGNGTTPH ASAGLGALNP GLYNPSASIL GGPSSSGASS
     VLPSPSAHTP DAATDANHLP NPDPASGRQE LTRAGRPARK KMKATALDAA LRTEMPNWPS
     VQDDFVRWTR LAWFEAGFAS TISDGAIGVQ TRRPFSPFLT TTFAQVGVHL PSMSPNLLRA
     FNSWVDMHLR SLRDHFKGRI DKPHAGKASL AARSLEDTTF VSLTEFINNM CNSYNLINSE
     LSVAAVRALC KLYLNVRNMA TAKDSEGVLR VHIRDASNRQ PPNILRGTLP QDREDDDLLT
     LITECGAIDF DLPTDTSDTM ALAVLMVMST SATTLTLDQA GCFSSLSGAA SAQVNLLTNV
     TCEWFSVTMV TESGTSTISL PSSTRPSAHI SAHGKDFALS WPKITEGLEI DIGLTLELQH
     NVTLDAYELR AKVVNHRPKA KASLWQLELN LRNVRQPEDG SAFFPAGYGV RYQGAFAASG
     SYPSSGATMQ WMAAGGGAAN EGQGLYLAAH DGYGYIKFLN AAAVEDVASL SIVYLVEDAG
     LPFAESTMPF PLTLAVVGGG DDLWYQAAQM YRTFALGEAQ WMQAGRLHQR QDIPGWYVNN
     SIWINSGWQC HDIFNETQGD PHTVLNVTRR IRERFNTNMA LHWYEWQQGP DANASARYRF
     DTHYPDYLPP RGGDYFGTVV RELEKEGVHI FPYINGRIFD VASTSYAQHN GSDHCCRKAN
     PSFGAADQSF YVESYGSGST FHTADPTDIY WQTTLADTVD ALVNTYGVEG VYIDQLAAAA
     PTPDWTSWHN HTKGGGFYWR TGIVDIIKAM RQRVGPTVPL VTESNSEPYM DAISGFLTLV
     AFEPAFVGTK ALVPAFPAIY GGYFVGFGDI FNAEDLADQD PLMARVVAQF VYGAQLGWFS
     LGGVTSGPDV DTSCGKMGEY DLWMSESSDA IVAAVEYYGN LRVCLLEYLA HGRILAPPSL
     SPAPAEFMAV ETAVQNAGPF PSAMSAVWLH EDEASAVIIV AGVLDAGQTY NVSVDLTFSL
     PSLHDRQVTV QEMSCDGLSQ QLDVMPANDI QIYDVTLSDR NARVYRVHFG A