GID8_ARATH
ID GID8_ARATH Reviewed; 243 AA.
AC Q84WK5; A8MQF1; O22730; Q3E7M2;
DT 25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Protein GID8 homolog {ECO:0000305};
GN Name=GID8 {ECO:0000305};
GN OrderedLocusNames=At1g61150 {ECO:0000312|Araport:AT1G61150};
GN ORFNames=F11P17.12 {ECO:0000312|EMBL:AAB71479.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY, INTERACTION WITH RANBPM, AND
RP SUBCELLULAR LOCATION.
RX PubMed=22676313; DOI=10.1186/1471-2229-12-83;
RA Tomastikova E., Cenklova V., Kohoutova L., Petrovska B., Vachova L.,
RA Halada P., Kocarova G., Binarova P.;
RT "Interactions of an Arabidopsis RanBPM homologue with LisH-CTLH domain
RT proteins revealed high conservation of CTLH complexes in eukaryotes.";
RL BMC Plant Biol. 12:83-83(2012).
CC -!- SUBUNIT: Interacts with RANBPM. {ECO:0000269|PubMed:22676313}.
CC -!- INTERACTION:
CC Q84WK5; Q9ZR37: DSPTP1; NbExp=3; IntAct=EBI-4466510, EBI-25512239;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:22676313}.
CC Note=Associates predominantly in the form of large cytoplasmic
CC complexes. {ECO:0000269|PubMed:22676313}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q84WK5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q84WK5-2; Sequence=VSP_059164;
CC -!- SIMILARITY: Belongs to the GID8 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB71479.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC002294; AAB71479.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33789.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33791.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33792.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33794.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM60212.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM60213.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM60214.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM60215.1; -; Genomic_DNA.
DR EMBL; BT003122; AAO24554.1; -; mRNA.
DR EMBL; AK317144; BAH19830.1; -; mRNA.
DR EMBL; AK228143; BAF00099.1; -; mRNA.
DR PIR; D96637; D96637.
DR RefSeq; NP_001077750.1; NM_001084281.2. [Q84WK5-2]
DR RefSeq; NP_001077752.1; NM_001084283.2. [Q84WK5-2]
DR RefSeq; NP_001319279.1; NM_001333936.1. [Q84WK5-2]
DR RefSeq; NP_001322513.1; NM_001333935.1. [Q84WK5-1]
DR RefSeq; NP_001322514.1; NM_001333934.1. [Q84WK5-1]
DR RefSeq; NP_001322515.1; NM_001333937.1. [Q84WK5-2]
DR RefSeq; NP_176310.3; NM_104796.5. [Q84WK5-1]
DR RefSeq; NP_974061.1; NM_202332.3. [Q84WK5-2]
DR AlphaFoldDB; Q84WK5; -.
DR SMR; Q84WK5; -.
DR IntAct; Q84WK5; 2.
DR STRING; 3702.AT1G61150.1; -.
DR PaxDb; Q84WK5; -.
DR PRIDE; Q84WK5; -.
DR ProteomicsDB; 221889; -. [Q84WK5-1]
DR EnsemblPlants; AT1G61150.1; AT1G61150.1; AT1G61150. [Q84WK5-1]
DR EnsemblPlants; AT1G61150.10; AT1G61150.10; AT1G61150. [Q84WK5-1]
DR EnsemblPlants; AT1G61150.11; AT1G61150.11; AT1G61150. [Q84WK5-1]
DR EnsemblPlants; AT1G61150.2; AT1G61150.2; AT1G61150. [Q84WK5-2]
DR EnsemblPlants; AT1G61150.4; AT1G61150.4; AT1G61150. [Q84WK5-2]
DR EnsemblPlants; AT1G61150.6; AT1G61150.6; AT1G61150. [Q84WK5-2]
DR EnsemblPlants; AT1G61150.8; AT1G61150.8; AT1G61150. [Q84WK5-2]
DR EnsemblPlants; AT1G61150.9; AT1G61150.9; AT1G61150. [Q84WK5-2]
DR GeneID; 842408; -.
DR Gramene; AT1G61150.1; AT1G61150.1; AT1G61150. [Q84WK5-1]
DR Gramene; AT1G61150.10; AT1G61150.10; AT1G61150. [Q84WK5-1]
DR Gramene; AT1G61150.11; AT1G61150.11; AT1G61150. [Q84WK5-1]
DR Gramene; AT1G61150.2; AT1G61150.2; AT1G61150. [Q84WK5-2]
DR Gramene; AT1G61150.4; AT1G61150.4; AT1G61150. [Q84WK5-2]
DR Gramene; AT1G61150.6; AT1G61150.6; AT1G61150. [Q84WK5-2]
DR Gramene; AT1G61150.8; AT1G61150.8; AT1G61150. [Q84WK5-2]
DR Gramene; AT1G61150.9; AT1G61150.9; AT1G61150. [Q84WK5-2]
DR KEGG; ath:AT1G61150; -.
DR Araport; AT1G61150; -.
DR TAIR; locus:2008460; AT1G61150.
DR eggNOG; KOG2659; Eukaryota.
DR HOGENOM; CLU_073203_1_0_1; -.
DR InParanoid; Q84WK5; -.
DR OrthoDB; 1365635at2759; -.
DR PhylomeDB; Q84WK5; -.
DR PRO; PR:Q84WK5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q84WK5; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR InterPro; IPR013144; CRA_dom.
DR InterPro; IPR024964; CTLH/CRA.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR006594; LisH.
DR Pfam; PF10607; CLTH; 1.
DR Pfam; PF08513; LisH; 1.
DR SMART; SM00757; CRA; 1.
DR SMART; SM00668; CTLH; 1.
DR SMART; SM00667; LisH; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS50896; LISH; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Cytoplasm; Reference proteome.
FT CHAIN 1..243
FT /note="Protein GID8 homolog"
FT /id="PRO_0000442060"
FT DOMAIN 40..72
FT /note="LisH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00126"
FT DOMAIN 78..135
FT /note="CTLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00058"
FT VAR_SEQ 1..17
FT /note="Missing (in isoform 2)"
FT /id="VSP_059164"
SQ SEQUENCE 243 AA; 27786 MW; E60F795DCF18A6F2 CRC64;
MSLFRIFINQ LEEDDEDMAT SKKMITREEW EKKLNAVKLR KEDMNTLVMN FLVTEGYVEA
AEKFQRESGT KPEIDLATIT DRMAVKKAVQ NGNVEDAIEK VNDLNPEILD TNPELFFHLQ
QQRLIELIRQ GKTEEALEFA QEELAPRGEE NQAFLEELEK TVALLVFDDA STCPVKELLD
LSHRLKTASE VNAAILTSQS HEKDPKLPSL LKMLIWAQTQ LDEKAVYPHI NDLSTGKLED
PSE
