GIF1_MAIZE
ID GIF1_MAIZE Reviewed; 227 AA.
AC A5HEH4; A0A2P0ZUD0;
DT 05-DEC-2018, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=GRF-interacting factor 1 {ECO:0000303|Ref.1};
DE Short=ZmGIF1 {ECO:0000303|Ref.1};
DE AltName: Full=Protein ANGUSTIFOLIA 3 homolog {ECO:0000303|PubMed:26036253};
GN Name=GIF1 {ECO:0000303|Ref.1}; Synonyms=AN3 {ECO:0000303|PubMed:26036253};
GN ORFNames=ZEAMMB73_Zm00001d033905 {ECO:0000312|EMBL:ONM08905.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RX AGRICOLA=IND44119307; DOI=10.1016/j.plantsci.2008.08.002;
RA Zhang D.F., Li B., Jia G.Q., Zhang T.F., Dai J.R., Li J.S., Wang S.C.;
RT "Isolation and characterization of genes encoding GRF transcription factors
RT and GIF transcriptional coactivators in Maize (Zea mays L.).";
RL Plant Sci. 175:809-817(2008).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, INTERACTION WITH GRF10, TISSUE
RP SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=29437990; DOI=10.1105/tpc.17.00791;
RA Zhang D., Sun W., Singh R., Zheng Y., Cao Z., Li M., Lunde C., Hake S.,
RA Zhang Z.;
RT "GRF-interacting factor1 regulates shoot architecture and meristem
RT determinacy in maize.";
RL Plant Cell 30:360-374(2018).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73;
RX PubMed=19965430; DOI=10.1126/science.1178534;
RA Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT "The B73 maize genome: complexity, diversity, and dynamics.";
RL Science 326:1112-1115(2009).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=18937034; DOI=10.1007/s11103-008-9415-4;
RA Alexandrov N.N., Brover V.V., Freidin S., Troukhan M.E., Tatarinova T.V.,
RA Zhang H., Swaller T.J., Lu Y.-P., Bouck J., Flavell R.B., Feldmann K.A.;
RT "Insights into corn genes derived from large-scale cDNA sequencing.";
RL Plant Mol. Biol. 69:179-194(2009).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. B73;
RX PubMed=19936069; DOI=10.1371/journal.pgen.1000740;
RA Soderlund C., Descour A., Kudrna D., Bomhoff M., Boyd L., Currie J.,
RA Angelova A., Collura K., Wissotski M., Ashley E., Morrow D., Fernandes J.,
RA Walbot V., Yu Y.;
RT "Sequencing, mapping, and analysis of 27,455 maize full-length cDNAs.";
RL PLoS Genet. 5:E1000740-E1000740(2009).
RN [6]
RP INTERACTION WITH GRF1 AND GRF10.
RX PubMed=24854713; DOI=10.1111/jipb.12220;
RA Wu L., Zhang D., Xue M., Qian J., He Y., Wang S.;
RT "Overexpression of the maize GRF10, an endogenous truncated growth-
RT regulating factor protein, leads to reduction in leaf size and plant
RT height.";
RL J. Integr. Plant Biol. 56:1053-1063(2014).
RN [7]
RP FUNCTION, AND INTERACTION WITH GRF.
RX PubMed=26036253; DOI=10.1105/tpc.15.00269;
RA Nelissen H., Eeckhout D., Demuynck K., Persiau G., Walton A., van Bel M.,
RA Vervoort M., Candaele J., De Block J., Aesaert S., Van Lijsebettens M.,
RA Goormachtig S., Vandepoele K., Van Leene J., Muszynski M., Gevaert K.,
RA Inze D., De Jaeger G.;
RT "Dynamic changes in ANGUSTIFOLIA3 complex composition reveal a growth
RT regulatory mechanism in the maize leaf.";
RL Plant Cell 27:1605-1619(2015).
CC -!- FUNCTION: Transcription coactivator that plays a role in the regulation
CC of meristematic function in leaves, stems and inflorescences
CC (PubMed:29437990). Regulates shoot architecture and meristem
CC determinacy (PubMed:29437990). Binds to the inflorescence architecture
CC gene UB3 (unbranched3) (PubMed:29437990). Regulates the expression of
CC several genes involved in inflorescence architecture (PubMed:29437990).
CC Component of a network formed by the microRNA396 (miRNA396), the GRFs
CC and their interacting factors (GIFs) acting in the regulation of
CC meristem function, at least partially through the control of cell
CC proliferation (Probable) (PubMed:26036253). Associates with the core
CC SWI/SNF chromatin-remodeling complex and specific GRFs to tightly
CC regulate the transition between cell division and cell expansion in
CC growing leaves (PubMed:26036253). {ECO:0000269|PubMed:26036253,
CC ECO:0000269|PubMed:29437990, ECO:0000305|PubMed:29437990}.
CC -!- SUBUNIT: Interacts with several GRFs (PubMed:29437990,
CC PubMed:26036253). Interacts with GRF10 (PubMed:29437990,
CC PubMed:24854713). Interacts with GRF1 (PubMed:24854713).
CC {ECO:0000269|PubMed:24854713, ECO:0000269|PubMed:26036253,
CC ECO:0000269|PubMed:29437990}.
CC -!- TISSUE SPECIFICITY: Expressed in shoots, aerial roots, ears and tassels
CC (Ref.1). Expressed in the shoot apical meristem (SAM), young leaf
CC primordia, leaf margins, inflorescence meristem, floral meristem and
CC spikelet meristem (PubMed:29437990). {ECO:0000269|PubMed:29437990,
CC ECO:0000269|Ref.1}.
CC -!- DISRUPTION PHENOTYPE: Dwarf plants with narrow and small leaves,
CC reduced number of branches in the tassel leaves, fasciated ears and
CC sterile florets. {ECO:0000269|PubMed:29437990}.
CC -!- SIMILARITY: Belongs to the SS18 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AVI00625.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; EF515854; ABQ01228.1; -; mRNA.
DR EMBL; MG893020; AVI00625.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CM007647; ONM08905.1; -; Genomic_DNA.
DR EMBL; EU960283; ACG32401.1; -; mRNA.
DR EMBL; BT037547; ACF82552.1; -; mRNA.
DR EMBL; BT042240; ACF87245.1; -; mRNA.
DR RefSeq; NP_001106030.1; NM_001112560.1.
DR AlphaFoldDB; A5HEH4; -.
DR SMR; A5HEH4; -.
DR STRING; 4577.GRMZM2G180246_P01; -.
DR PaxDb; A5HEH4; -.
DR EnsemblPlants; Zm00001eb056300_T001; Zm00001eb056300_P001; Zm00001eb056300.
DR GeneID; 100101544; -.
DR Gramene; Zm00001eb056300_T001; Zm00001eb056300_P001; Zm00001eb056300.
DR KEGG; zma:100101544; -.
DR eggNOG; KOG3227; Eukaryota.
DR HOGENOM; CLU_086253_0_0_1; -.
DR OMA; MYAQPAL; -.
DR OrthoDB; 1495963at2759; -.
DR Proteomes; UP000007305; Chromosome 1.
DR ExpressionAtlas; A5HEH4; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblPlants.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003713; F:transcription coactivator activity; IEA:InterPro.
DR GO; GO:0009955; P:adaxial/abaxial pattern specification; IEA:EnsemblPlants.
DR GO; GO:0051301; P:cell division; IEA:EnsemblPlants.
DR GO; GO:0008283; P:cell population proliferation; IMP:UniProtKB.
DR GO; GO:0048825; P:cotyledon development; IEA:EnsemblPlants.
DR GO; GO:0010582; P:floral meristem determinacy; IMP:UniProtKB.
DR GO; GO:0048366; P:leaf development; IMP:UniProtKB.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR GO; GO:0010449; P:root meristem growth; IEA:EnsemblPlants.
DR InterPro; IPR044779; SS18.
DR InterPro; IPR007726; SS18_N.
DR PANTHER; PTHR23107; PTHR23107; 1.
DR Pfam; PF05030; SSXT; 1.
PE 1: Evidence at protein level;
KW Activator; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..227
FT /note="GRF-interacting factor 1"
FT /id="PRO_0000445645"
FT REGION 186..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 227 AA; 23603 MW; 6B859564B547D737 CRC64;
MQQQHLMQMN QNMMGGYTSP AAVTTDLIQQ YLDENKQLIL AILDNQNNGK AEECERHQAK
LQHNLMYLAA IADSQPPQTA PLSQYPSNLM MQPGPRYMPP QSGQMMNPQS LMAARSSMMY
AHPSLSPLQQ QQAAHGQLGM APGGGGGGTT SGFSILHGEA SMGGGGAGAG AGNNMMNAGM
FSGFGRSGSG AKEGSTSLSV DVRGGTSSGA QSGDGEYLKV GTEEEGS
