ID   GIMA6_BOVIN             Reviewed;         341 AA.
AC   A5PKB7;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=GTPase IMAP family member 6;
DE   AltName: Full=Immunity-associated nucleotide 6 protein;
DE            Short=IAN-6;
GN   Name=GIMAP6; Synonyms=IAN6;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:Q6P9H5}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC       IAN subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC142429; AAI42430.1; -; mRNA.
DR   RefSeq; NP_001093182.1; NM_001099712.1.
DR   AlphaFoldDB; A5PKB7; -.
DR   SMR; A5PKB7; -.
DR   PRIDE; A5PKB7; -.
DR   GeneID; 528288; -.
DR   CTD; 474344; -.
DR   InParanoid; A5PKB7; -.
DR   OrthoDB; 1092873at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005829; C:cytosol; ISS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR006703; G_AIG1.
DR   InterPro; IPR045058; GIMA/IAN/Toc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10903; PTHR10903; 1.
DR   Pfam; PF04548; AIG1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51720; G_AIG1; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; GTP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..341
FT                   /note="GTPase IMAP family member 6"
FT                   /id="PRO_0000333010"
FT   DOMAIN          91..294
FT                   /note="AIG1-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT   REGION          28..85
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          100..107
FT                   /note="G1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT   REGION          127..131
FT                   /note="G2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT   REGION          148..151
FT                   /note="G3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT   REGION          217..220
FT                   /note="G4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT   REGION          254..256
FT                   /note="G5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT   COMPBIAS        35..59
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         100..108
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:Q8WWP7"
FT   BINDING         121
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UG22"
FT   BINDING         218..220
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:Q8WWP7"
FT   BINDING         255
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:Q8WWP7"
SQ   SEQUENCE   341 AA;  37305 MW;  2BA34CC3391CBE75 CRC64;
     MSSMFVYVWG TVTDLLHSAC SVLALNGDTE SSGEHTAPGD TRHGHSSCPT DSRAMEEEEF
     EILLPEEPEE GTSQDPSPDR SGGFLGDEGT LQTLWLILVG KSGSGKSATG NSILGRRVFE
     SKLSARPVTQ AFQQGCRAWE GRELQVIDTP DILSPWAAGW ATAQGVGEAG TGSLPKQYAV
     LLVTQLGRFT EEDQQVAGRL EEVFGKGILA RTILVFTRKE DLDGRSLETY LRETDNRALA
     KLDDVCSRRH CGFNNKGDGA EQETQLRELM RHVEGVLKEP EGCAYSPPAT PQPHAAPRES
     WGLWWLGAKE GRGDQAWLWG LHRILKEPEQ AGRQLPPSTP I