ID   GIMD1_MOUSE             Reviewed;         217 AA.
AC   E9PW74;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   05-APR-2011, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=GTPase IMAP family member GIMD1;
DE   AltName: Full=GIMAP family P-loop NTPase domain-containing protein 1;
GN   Name=Gimd1; Synonyms=Gm5549;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Liver;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC       IAN subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC122851; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS57257.1; -.
DR   RefSeq; NP_001257359.1; NM_001270430.1.
DR   RefSeq; XP_006501712.2; XM_006501649.2.
DR   AlphaFoldDB; E9PW74; -.
DR   SMR; E9PW74; -.
DR   PhosphoSitePlus; E9PW74; -.
DR   MaxQB; E9PW74; -.
DR   PaxDb; E9PW74; -.
DR   PeptideAtlas; E9PW74; -.
DR   PRIDE; E9PW74; -.
DR   ProteomicsDB; 271223; -.
DR   Ensembl; ENSMUST00000163241; ENSMUSP00000126832; ENSMUSG00000091721.
DR   Ensembl; ENSMUST00000196701; ENSMUSP00000142630; ENSMUSG00000091721.
DR   Ensembl; ENSMUST00000212594; ENSMUSP00000148464; ENSMUSG00000091721.
DR   Ensembl; ENSMUST00000212804; ENSMUSP00000148832; ENSMUSG00000091721.
DR   GeneID; 433653; -.
DR   KEGG; mmu:433653; -.
DR   UCSC; uc033hzy.1; mouse.
DR   CTD; 100507096; -.
DR   MGI; MGI:3647547; Gimd1.
DR   VEuPathDB; HostDB:ENSMUSG00000091721; -.
DR   eggNOG; ENOG502S1B7; Eukaryota.
DR   GeneTree; ENSGT00530000069080; -.
DR   HOGENOM; CLU_010468_3_3_1; -.
DR   InParanoid; E9PW74; -.
DR   OMA; WKDFTAV; -.
DR   OrthoDB; 1084829at2759; -.
DR   PhylomeDB; E9PW74; -.
DR   BioGRID-ORCS; 433653; 1 hit in 32 CRISPR screens.
DR   PRO; PR:E9PW74; -.
DR   Proteomes; UP000000589; Chromosome 3.
DR   RNAct; E9PW74; protein.
DR   Bgee; ENSMUSG00000091721; Expressed in duodenum and 14 other tissues.
DR   ExpressionAtlas; E9PW74; baseline and differential.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR006703; G_AIG1.
DR   InterPro; IPR045058; GIMA/IAN/Toc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10903; PTHR10903; 1.
DR   Pfam; PF04548; AIG1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51720; G_AIG1; 1.
PE   1: Evidence at protein level;
KW   GTP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..217
FT                   /note="GTPase IMAP family member GIMD1"
FT                   /id="PRO_0000419200"
FT   DOMAIN          6..217
FT                   /note="AIG1-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01057"
FT   BINDING         15..23
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         36
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         148..150
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   217 AA;  24219 MW;  412D34DCC3DB6851 CRC64;
     MTDTNKMIIN LAVFGRTQSG KSSAGNVLLG SADFYSSFAP GSVTKECSLG RSCHLHGFMR
     RGGQEISLQI QVLDTPGYPH SKLSTRCVKQ EVKKALLHHF GQEGLHLALL VQRADVPFFG
     QEASNAVQLM QELLGDSCKN YMAVLFTHAE ELEEAGLSEE EYLREASDTL LTLLDSVQHR
     YIFLSGRGNL CNEQRIKILE RIMEFIKENH FQVLSLA