ID   GINM1_DANRE             Reviewed;         352 AA.
AC   Q5RII3; A5PL58; Q5RFZ5;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Glycoprotein integral membrane protein 1;
DE   Flags: Precursor;
GN   Name=ginm1; ORFNames=si:ch211-87e4.1, si:dkey-15j16.2;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BX255904; CAI20704.1; -; Genomic_DNA.
DR   EMBL; CR388170; CAI12050.1; -; Genomic_DNA.
DR   EMBL; BC142753; AAI42754.1; -; mRNA.
DR   EMBL; BC155128; AAI55129.1; -; mRNA.
DR   RefSeq; NP_001073305.1; NM_001079836.1.
DR   AlphaFoldDB; Q5RII3; -.
DR   SMR; Q5RII3; -.
DR   STRING; 7955.ENSDARP00000039045; -.
DR   PaxDb; Q5RII3; -.
DR   PRIDE; Q5RII3; -.
DR   Ensembl; ENSDART00000032393; ENSDARP00000039045; ENSDARG00000021975.
DR   GeneID; 555775; -.
DR   KEGG; dre:555775; -.
DR   CTD; 116254; -.
DR   ZFIN; ZDB-GENE-030131-5900; ginm1.
DR   eggNOG; ENOG502RWUZ; Eukaryota.
DR   GeneTree; ENSGT00390000008373; -.
DR   HOGENOM; CLU_084379_0_0_1; -.
DR   InParanoid; Q5RII3; -.
DR   OMA; HQWPLAS; -.
DR   OrthoDB; 1093788at2759; -.
DR   PhylomeDB; Q5RII3; -.
DR   TreeFam; TF333227; -.
DR   PRO; PR:Q5RII3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 20.
DR   Bgee; ENSDARG00000021975; Expressed in swim bladder and 24 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR042319; GINM1.
DR   PANTHER; PTHR28549; PTHR28549; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..352
FT                   /note="Glycoprotein integral membrane protein 1"
FT                   /id="PRO_0000360403"
FT   TOPO_DOM        26..281
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        303..352
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          206..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        229..245
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        36
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        44
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        89
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        109
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        151
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        197
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        95
FT                   /note="S -> T (in Ref. 2; AAI42754/AAI55129)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        244
FT                   /note="D -> N (in Ref. 2; AAI42754/AAI55129)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        307
FT                   /note="L -> V (in Ref. 2; AAI42754/AAI55129)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   352 AA;  39274 MW;  6F65C93DC2BA83CD CRC64;
     MASRCKIHLT VAYLLILCIL ASAQSKQMTT ETVVLNVTAL SEINQTKYNV QINLNIGLLD
     NDIFINGAPL KPSGVTRMTC PALLLDGYNV SSGNSVDGLV SCELRLMVNQ SYVQSDAAEQ
     LLFLVLSQEI IQLADEKVQQ PEISEVEIMW NQSSEQMTQV TSIYPSARSK LSIIPRENDV
     LVTDASVQSA VEDQVRNTTS HYLLKNSETT QEEIAAPGKL PETPLRMDPE TLYESREEEE
     RRSDSLLLEP PLSGSMSSYS VACQWVEKLR DKLRRFLSDS VPLFFLVMWV VVVGVAGSAV
     VIKILDLIFP SCEHRGFFHL NPETLMPDDE KVSLIDNMEG DMTEKSILLI EK