ID   GIP4_KLULA              Reviewed;         757 AA.
AC   Q6CLJ6;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=GLC7-interacting protein 4;
GN   Name=GIP4; OrderedLocusNames=KLLA0F02497g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: GLC7 phosphatase-regulatory protein involved in GLC7
CC       subcellular redistribution and chromosome segregation. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with GLC7. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GIP4 family. {ECO:0000305}.
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DR   EMBL; CR382126; CAG97900.1; -; Genomic_DNA.
DR   RefSeq; XP_455193.1; XM_455193.1.
DR   AlphaFoldDB; Q6CLJ6; -.
DR   SMR; Q6CLJ6; -.
DR   STRING; 28985.XP_455193.1; -.
DR   EnsemblFungi; CAG97900; CAG97900; KLLA0_F02497g.
DR   GeneID; 2894912; -.
DR   KEGG; kla:KLLA0_F02497g; -.
DR   eggNOG; ENOG502QRIU; Eukaryota.
DR   HOGENOM; CLU_021324_0_0_1; -.
DR   InParanoid; Q6CLJ6; -.
DR   OMA; WYKKPAV; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; IEA:InterPro.
DR   GO; GO:0019888; F:protein phosphatase regulator activity; IEA:InterPro.
DR   InterPro; IPR026241; GIP4.
DR   PRINTS; PR02082; GLC7IP4.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..757
FT                   /note="GLC7-interacting protein 4"
FT                   /id="PRO_0000292484"
FT   REGION          427..541
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          558..590
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        440..501
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        509..541
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        566..590
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   757 AA;  85401 MW;  033CE88E374D49F6 CRC64;
     MLAKAAASAS SSMEKGSVYL DFTDIKCIQY TSSIRKLEQL VHVCKVLLRN LSMKSNENLI
     PLSNIVIALG SGFQFNVSAA IEKRIELLSQ FRSCKANATN LPLSTTSLKL EVDLVPVEED
     SVLFVSKFYN KELQSQLLTT LQRVAEDSLQ IYQARIRQLT MERNSNRPTD LSGRTTIFNE
     DALNDLLSPN ELAFGLDLLV NIRNRSTDTS SSAFFALALP ILEKFRSNLN DKCIPPIRSY
     YTSIMKFSRT KGVFSNNVLI QLPYWQFTLH RMYAASLRAK CLIDVIRAVL RQIYIPNKHH
     FHDNTTKLHS KNLHEYSELL EELETFCFTQ ELEKDLIEAF KSYGNQNTVY QVQFNNISSA
     YQRLLLKSTQ MLRKAAKLVD SFSTQWKSIS DNMKASKYDD MNIDEMAKMA EEKLAVDELA
     YNEKIKEQER QREEKKNSSL SQKNTSSSSS ITSNSSSLNV SPNILSPLRL SRTSSVSRSE
     ESRSPSSPIP FTDAKSNISA KKTRSVRTRN RSSSLQSVSS LEDTSTARNG MRSNSLQSGS
     LNTQRIVQNA YSKALLSLNE KRGPRLTPTK LNNSIRSKSP SPTVSRQNSV KQRNKVNILK
     LNEVDEDDIN EKFHDLKLDD DTLIVSQEVL SPEGSETPKI IVSVADDNQS SSNNDSEVEG
     IVKKVRFIGV PPMSQDENPE PKRRGWYKKP AVLHYPPPPA QHSLQKFRTT QEGLAFRTSL
     ISRDQGSDKK FGFDSMYSSG QGADTKIVGK IKDKLFK