ID   GIPC2_RAT               Reviewed;         314 AA.
AC   Q498D9;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=PDZ domain-containing protein GIPC2;
GN   Name=Gipc2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Placenta;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Probably interacts with SEMA5A. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GIPC family. {ECO:0000305}.
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DR   EMBL; BC100257; AAI00258.1; -; mRNA.
DR   RefSeq; NP_001032287.1; NM_001037210.1.
DR   AlphaFoldDB; Q498D9; -.
DR   SMR; Q498D9; -.
DR   STRING; 10116.ENSRNOP00000063118; -.
DR   PaxDb; Q498D9; -.
DR   PRIDE; Q498D9; -.
DR   Ensembl; ENSRNOT00000065811; ENSRNOP00000063118; ENSRNOG00000042152.
DR   GeneID; 365960; -.
DR   KEGG; rno:365960; -.
DR   CTD; 54810; -.
DR   RGD; 1560751; Gipc2.
DR   eggNOG; KOG3938; Eukaryota.
DR   GeneTree; ENSGT00390000003420; -.
DR   InParanoid; Q498D9; -.
DR   OrthoDB; 1442796at2759; -.
DR   PhylomeDB; Q498D9; -.
DR   PRO; PR:Q498D9; -.
DR   Proteomes; UP000002494; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042802; F:identical protein binding; ISO:RGD.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR017379; GIPC1/2/3.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR12259; PTHR12259; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   PIRSF; PIRSF038083; UCP038083_GIPC; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   PROSITE; PS50106; PDZ; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..314
FT                   /note="PDZ domain-containing protein GIPC2"
FT                   /id="PRO_0000247190"
FT   DOMAIN          117..197
FT                   /note="PDZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   314 AA;  34202 MW;  E782A80064E795FC CRC64;
     MPLGLRGKKK AAKSKETARL VEGERSGGSQ GVPGPPAPAR RLVFHAQLAH GSATGRVEDF
     SSISELYAKI AGVFEIAPSE ILFCTLNTPK IDMGKLLGGQ LGLEDFIFAH VKGIKKEVNV
     YKSEDSLGLT ITDNGVGYAF IKRIKDGSTI DSVKTICVGD HIECINGENI VGWRHFEVAK
     KLKELKKEEL FTLQLIEPKK AFEIGPRSKA GKTSTEKIGT SRGTLRLRSK GPATVEDLPS
     EAKAKAIEKV DDLLELYMGI RDIDLATTMF EAGKDKSNPD EFAVALDETL GDFAFPDEFM
     FDVWGAISDV KQGR