ID   GKAP1_DANRE             Reviewed;         368 AA.
AC   Q6NWC9; Q503P0; Q7SYM2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=G kinase-anchoring protein 1;
GN   Name=gkap1; ORFNames=zgc:85804;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB; TISSUE=Kidney;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the regulation of insulin-dependent IRS1
CC       tyrosine phosphorylation in adipocytes. {ECO:0000250|UniProtKB:Q9JMB0}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:Q9JMB0}.
CC   -!- SIMILARITY: Belongs to the GKAP1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH95240.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; BC054663; AAH54663.1; -; mRNA.
DR   EMBL; BC067639; AAH67639.1; -; mRNA.
DR   EMBL; BC095240; AAH95240.1; ALT_FRAME; mRNA.
DR   RefSeq; NP_998237.1; NM_213072.2.
DR   RefSeq; XP_005167378.1; XM_005167321.3.
DR   AlphaFoldDB; Q6NWC9; -.
DR   SMR; Q6NWC9; -.
DR   STRING; 7955.ENSDARP00000012352; -.
DR   PaxDb; Q6NWC9; -.
DR   PRIDE; Q6NWC9; -.
DR   Ensembl; ENSDART00000098319; ENSDARP00000089091; ENSDARG00000068123.
DR   GeneID; 406581; -.
DR   KEGG; dre:406581; -.
DR   CTD; 80318; -.
DR   ZFIN; ZDB-GENE-040426-2485; gkap1.
DR   eggNOG; ENOG502QUT6; Eukaryota.
DR   GeneTree; ENSGT00390000008742; -.
DR   HOGENOM; CLU_065161_1_0_1; -.
DR   InParanoid; Q6NWC9; -.
DR   OMA; RKNHQGR; -.
DR   OrthoDB; 1595194at2759; -.
DR   PhylomeDB; Q6NWC9; -.
DR   TreeFam; TF328459; -.
DR   PRO; PR:Q6NWC9; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 8.
DR   Bgee; ENSDARG00000068123; Expressed in mature ovarian follicle and 26 other tissues.
DR   ExpressionAtlas; Q6NWC9; baseline.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   InterPro; IPR026109; GKAP1.
DR   PANTHER; PTHR14899; PTHR14899; 1.
DR   PRINTS; PR02083; GKINASEAP1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Golgi apparatus; Reference proteome.
FT   CHAIN           1..368
FT                   /note="G kinase-anchoring protein 1"
FT                   /id="PRO_0000315657"
FT   REGION          18..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          152..260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          333..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          52..82
FT                   /evidence="ECO:0000255"
FT   COILED          256..350
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        90..120
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..240
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        338..368
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        15
FT                   /note="F -> L (in Ref. 1; AAH54663)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        261
FT                   /note="Q -> L (in Ref. 1; AAH95240)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        290
FT                   /note="V -> A (in Ref. 1; AAH54663)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   368 AA;  41960 MW;  97F3DD3077B9E568 CRC64;
     MASAVISVPT TASRFALLQV DSDSDSDSDV GKPKAAGRGA GKPRSGKSPS GKNSQNNEKK
     KEKRRRKKEQ QQSEANELRS LAFKKIPQKS TAPPSLTLQD LANDLINPAN VQQGSKPQEN
     WQEWKQRDEQ LTSDLYEADL EKALMLSKLE FEEHKKDADK AETASPKTKT GGKKDRKKNQ
     QGKDKRVTVS LKDFQQEDQL KNKPEREPVN PALRDDKFFN KLEDDVSKIV QRDKRREQYS
     NSAGQEVNTS SEHEQDVRTE QLKYELEKKD QEIAKLKKTI SQWEERYKEV KARNSQLLKM
     LQQGEMKDKA EILLQVEELL NIKEELSSQV TQLHTALEQE RSKVKGLQSE QPKHQGNRKG
     KKASEGDV