ID   GKAP1_XENTR             Reviewed;         363 AA.
AC   Q5M8L3; Q0VFS6; Q66KB2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=G kinase-anchoring protein 1;
GN   Name=gkap1; ORFNames=TGas066g20.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the regulation of insulin-dependent IRS1
CC       tyrosine phosphorylation in adipocytes. {ECO:0000250|UniProtKB:Q9JMB0}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:Q9JMB0}.
CC   -!- SIMILARITY: Belongs to the GKAP1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH80476.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
CC       Sequence=AAI18717.1; Type=Frameshift; Evidence={ECO:0000305};
CC       Sequence=AAI18717.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
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DR   EMBL; CR761519; CAJ82599.1; -; mRNA.
DR   EMBL; BC080476; AAH80476.1; ALT_SEQ; mRNA.
DR   EMBL; BC087974; AAH87974.1; -; mRNA.
DR   EMBL; BC118716; AAI18717.1; ALT_SEQ; mRNA.
DR   RefSeq; NP_001011266.1; NM_001011266.1.
DR   AlphaFoldDB; Q5M8L3; -.
DR   SMR; Q5M8L3; -.
DR   STRING; 8364.ENSXETP00000057503; -.
DR   PaxDb; Q5M8L3; -.
DR   DNASU; 496717; -.
DR   GeneID; 496717; -.
DR   KEGG; xtr:496717; -.
DR   CTD; 80318; -.
DR   Xenbase; XB-GENE-1002568; gkap1.
DR   eggNOG; ENOG502QUT6; Eukaryota.
DR   HOGENOM; CLU_065161_1_0_1; -.
DR   InParanoid; Q5M8L3; -.
DR   OrthoDB; 1595194at2759; -.
DR   PhylomeDB; Q5M8L3; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000016759; Expressed in testis and 12 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   InterPro; IPR026109; GKAP1.
DR   PANTHER; PTHR14899; PTHR14899; 1.
DR   PRINTS; PR02083; GKINASEAP1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Golgi apparatus; Reference proteome.
FT   CHAIN           1..363
FT                   /note="G kinase-anchoring protein 1"
FT                   /id="PRO_0000315660"
FT   REGION          22..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          143..185
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          54..79
FT                   /evidence="ECO:0000255"
FT   COILED          247..298
FT                   /evidence="ECO:0000255"
FT   COILED          328..348
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        102..116
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        107
FT                   /note="Y -> S (in Ref. 2; AAH80476/AAI18717)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   363 AA;  41309 MW;  CE9A93C79C121196 CRC64;
     MASAVVSMVP TTASRFALLQ VDSSSDSDSE KARGAHATGK ARSGSAAKGK SKGNEKKKEK
     RRKKKEQQQS EANELRNLAF KKIPSKPSQG IGGALQEHST HNVPKEYQED DWQQWQQRDE
     QLTSDMFEAD LEKALMLSKL EYEESKDNGN EVNGVPQSKK VNKKDKRRNN QGKDKPLTVP
     LKDFQLEDQQ AKKQEELKSP AMPQDRGFFN KLEEDVTKII LKEKRKEHSS DVTESFSTPD
     YSMEPALKDG KTEVLKQEIE KKEAELKQMK SIISQWEAKY REVKARNSQL LKMLQEGEMK
     DKAEILLQVD ELLSIKNELT LQVTTLHAAL EQERSKVKVL QAEQVKYQGG KKSKKNPESE
     HGR