GL113_ARATH
ID GL113_ARATH Reviewed; 222 AA.
AC P92997; F4KD10;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 25-JAN-2012, sequence version 2.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Germin-like protein subfamily 1 member 13;
DE Flags: Precursor;
GN Name=GLP6; OrderedLocusNames=At5g39100; ORFNames=MXF12.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=9869400; DOI=10.1023/a:1006038117130;
RA Carter C., Graham R.A., Thornburg R.W.;
RT "Arabidopsis thaliana contains a large family of germin-like proteins:
RT characterization of cDNA and genomic sequences encoding 12 unique family
RT members.";
RL Plant Mol. Biol. 38:929-943(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: May play a role in plant defense. Probably has no oxalate
CC oxidase activity even if the active site is conserved.
CC -!- SUBUNIT: Oligomer (believed to be a pentamer but probably hexamer).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the germin family. {ECO:0000305}.
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DR EMBL; U75194; AAB51572.1; -; mRNA.
DR EMBL; AB016892; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED94394.2; -; Genomic_DNA.
DR RefSeq; NP_001318702.1; NM_001344284.1.
DR AlphaFoldDB; P92997; -.
DR SMR; P92997; -.
DR PRIDE; P92997; -.
DR GeneID; 833903; -.
DR KEGG; ath:AT5G39100; -.
DR Araport; AT5G39100; -.
DR InParanoid; P92997; -.
DR OrthoDB; 1164277at2759; -.
DR PRO; PR:P92997; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; P92997; baseline and differential.
DR GO; GO:0048046; C:apoplast; IEA:UniProtKB-SubCell.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR Gene3D; 2.60.120.10; -; 1.
DR InterPro; IPR006045; Cupin_1.
DR InterPro; IPR001929; Germin.
DR InterPro; IPR019780; Germin_Mn-BS.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR Pfam; PF00190; Cupin_1; 1.
DR PRINTS; PR00325; GERMIN.
DR SMART; SM00835; Cupin_1; 1.
DR SUPFAM; SSF51182; SSF51182; 1.
DR PROSITE; PS00725; GERMIN; 1.
PE 2: Evidence at transcript level;
KW Apoplast; Disulfide bond; Glycoprotein; Manganese; Metal-binding;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..222
FT /note="Germin-like protein subfamily 1 member 13"
FT /id="PRO_0000010813"
FT DOMAIN 63..214
FT /note="Cupin type-1"
FT /evidence="ECO:0000255"
FT BINDING 111
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT BINDING 113
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT BINDING 118
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT BINDING 160
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT CARBOHYD 78
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 32..49
FT /evidence="ECO:0000250"
FT CONFLICT 214
FT /note="E -> K (in Ref. 1; AAB51572)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 222 AA; 24095 MW; 967705F8096E4115 CRC64;
MRVSKSLILI TLSALVISFA EAYDPSPLQD FCVAIDDLKN GVFVNGKFCK DPKQAKAEDF
FFSGLNQAGS TNNKVRSNVT TVNVDQIPGL NTMGISLVRI DYAPYGQNPP HTHPRATEIL
VLIEGTLYVG FVSSNQDNNR LFAKVLYPGD VFVFPIGMIH FQVNIGKTPA VAFAGLSSQN
AGVITIADTV FGSTPPINPD ILAQAFQLDV NIVEDLEAKF RN
