GL19_ORYSJ
ID GL19_ORYSJ Reviewed; 186 AA.
AC P29835; P93414; Q0DH05;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 07-MAR-2006, sequence version 2.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=19 kDa globulin;
DE AltName: Full=Alpha-globulin;
DE AltName: Allergen=Ory s 19kD;
DE Flags: Precursor;
GN OrderedLocusNames=Os05g0499100, LOC_Os05g41970;
GN ORFNames=OJ1057_B02.5, OsJ_19079 {ECO:0000312|EMBL:EEE64246.1},
GN P0010D04.16;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC STRAIN=cv. Nipponbare; TISSUE=Endosperm;
RX PubMed=1731968; DOI=10.1007/bf00018470;
RA Shorrosh B.S., Wen L., Zen K.C., Huang J.K., Pan J.S., Hermodson M.A.,
RA Tanaka K., Muthukrishnan S., Reeck G.R.;
RT "A novel cereal storage protein: molecular genetics of the 19 kDa globulin
RT of rice.";
RL Plant Mol. Biol. 18:151-154(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC TISSUE=Endosperm;
RX PubMed=8666249; DOI=10.1016/0378-1119(95)00887-x;
RA Nakase M., Hotta H., Adachi T., Aoki N., Nakamura R., Masumura T.,
RA Tanaka K., Matsuda T.;
RT "Cloning of rhe rice seed alpha-globulin-encoding gene: sequence similarity
RT of the 5'-flanking region to those of the genes encoding wheat high
RT molecular-weight glutenin and barley D hordein.";
RL Gene 170:223-226(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Ilpoombyeo; TISSUE=Seed;
RA Yoon U.H., Kim Y.H.;
RT "Molecular cloning of alpha-globulin genes in rice seeds.";
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Ilpoombyeo; TISSUE=Seed;
RA Yoon U.H., Kim Y.H.;
RT "Structural and expression analysis of germinating seed genes in Oryza
RT sativa L.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [7]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [8]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [9]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [10]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [11]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 5-186.
RC STRAIN=cv. Lemont; TISSUE=Endosperm;
RX PubMed=8503935; DOI=10.1006/bbrc.1993.1646;
RA Krishnan H.B., Pueppke S.G.;
RT "Nucleotide sequence of an abundant rice seed globulin: homology with the
RT high molecular weight glutelins of wheat, rye and triticale.";
RL Biochem. Biophys. Res. Commun. 193:460-466(1993).
RN [12]
RP PROTEIN SEQUENCE OF 141-151.
RC STRAIN=cv. Nipponbare; TISSUE=Endosperm;
RX PubMed=14681440; DOI=10.1093/nar/gkh020;
RA Komatsu S., Kojima K., Suzuki K., Ozaki K., Higo K.;
RT "Rice proteome database based on two-dimensional polyacrylamide gel
RT electrophoresis: its status in 2003.";
RL Nucleic Acids Res. 32:D388-D392(2004).
RN [13]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND ALLERGEN.
RX PubMed=21300107; DOI=10.1016/j.yrtph.2011.01.008;
RA Satoh R., Nakamura R., Komatsu A., Oshima M., Teshima R.;
RT "Proteomic analysis of known and candidate rice allergens between non-
RT transgenic and transgenic plants.";
RL Regul. Toxicol. Pharmacol. 59:437-444(2011).
RN [14]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND ALLERGEN.
RX PubMed=24016103; DOI=10.1021/jf402759f;
RA Golias J., Humlova Z., Halada P., Habova V., Janatkova I., Tuckova L.;
RT "Identification of rice proteins recognized by the IgE antibodies of
RT patients with food allergies.";
RL J. Agric. Food Chem. 61:8851-8860(2013).
CC -!- FUNCTION: Seed storage protein. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE.
CC {ECO:0000269|PubMed:21300107, ECO:0000269|PubMed:24016103}.
CC -!- SIMILARITY: Belongs to the 2S seed storage albumins family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA72362.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; X63990; CAA45400.1; -; mRNA.
DR EMBL; D50643; BAA09308.1; -; Genomic_DNA.
DR EMBL; EF122478; ABL74565.1; -; mRNA.
DR EMBL; GQ848069; ADM86882.1; -; mRNA.
DR EMBL; AC113332; AAT93857.1; -; Genomic_DNA.
DR EMBL; AC130605; AAT44292.1; -; Genomic_DNA.
DR EMBL; AP008211; BAF17868.1; -; Genomic_DNA.
DR EMBL; AP014961; BAS94743.1; -; Genomic_DNA.
DR EMBL; CM000142; EEE64246.1; -; Genomic_DNA.
DR EMBL; AK242943; BAH01389.1; -; mRNA.
DR EMBL; L12252; AAA72362.1; ALT_INIT; mRNA.
DR PIR; JC4784; JC4784.
DR PIR; S20024; WMRZ19.
DR RefSeq; XP_015639142.1; XM_015783656.1.
DR AlphaFoldDB; P29835; -.
DR STRING; 4530.OS05T0499100-01; -.
DR Allergome; 9528; Ory s 19kD.
DR PaxDb; P29835; -.
DR PRIDE; P29835; -.
DR EnsemblPlants; Os05t0499100-01; Os05t0499100-01; Os05g0499100.
DR GeneID; 4339221; -.
DR Gramene; Os05t0499100-01; Os05t0499100-01; Os05g0499100.
DR KEGG; osa:4339221; -.
DR eggNOG; ENOG502R604; Eukaryota.
DR HOGENOM; CLU_1404429_0_0_1; -.
DR InParanoid; P29835; -.
DR OMA; RMRCCQQ; -.
DR OrthoDB; 1466684at2759; -.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000007752; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR Genevisible; P29835; OS.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0019863; F:IgE binding; IDA:UniProtKB.
DR GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR CDD; cd00261; AAI_SS; 1.
DR Gene3D; 1.10.110.10; -; 1.
DR InterPro; IPR044723; AAI_SS_dom.
DR InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR Pfam; PF00234; Tryp_alpha_amyl; 1.
DR SMART; SM00499; AAI; 1.
DR SUPFAM; SSF47699; SSF47699; 1.
PE 1: Evidence at protein level;
KW Allergen; Direct protein sequencing; Reference proteome; Secreted;
KW Seed storage protein; Signal; Storage protein.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..186
FT /note="19 kDa globulin"
FT /id="PRO_0000032161"
FT REGION 108..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 23..24
FT /note="QL -> HV (in Ref. 1; CAA45400 and 11; AAA72362)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 186 AA; 21055 MW; AE2B8F1107C8BC94 CRC64;
MASKVVFFAA ALMAAMVAIS GAQLSESEMR FRDRQCQREV QDSPLDACRQ VLDRQLTGRE
RFQPMFRRPG ALGLRMQCCQ QLQDVSRECR CAAIRRMVRS YEESMPMPLE QGWSSSSSEY
YGGEGSSSEQ GYYGEGSSEE GYYGEQQQQP GMTRVRLTRA RQYAAQLPSM CRVEPQQCSI
FAAGQY
