GL23_ARATH
ID GL23_ARATH Reviewed; 219 AA.
AC P93000;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1997, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Germin-like protein subfamily 2 member 3;
DE Flags: Precursor;
GN Name=GLP8; OrderedLocusNames=At3g05930; ORFNames=F10A16.23, F2O10.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=9869400; DOI=10.1023/a:1006038117130;
RA Carter C., Graham R.A., Thornburg R.W.;
RT "Arabidopsis thaliana contains a large family of germin-like proteins:
RT characterization of cDNA and genomic sequences encoding 12 unique family
RT members.";
RL Plant Mol. Biol. 38:929-943(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: May play a role in plant defense. Probably has no oxalate
CC oxidase activity even if the active site is conserved.
CC -!- SUBUNIT: Oligomer (believed to be a pentamer but probably hexamer).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the germin family. {ECO:0000305}.
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DR EMBL; U75207; AAB51585.1; -; mRNA.
DR EMBL; AC012393; AAF26095.1; -; Genomic_DNA.
DR EMBL; AC013454; AAF23223.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74317.1; -; Genomic_DNA.
DR RefSeq; NP_187244.1; NM_111467.3.
DR AlphaFoldDB; P93000; -.
DR SMR; P93000; -.
DR STRING; 3702.AT3G05930.1; -.
DR PaxDb; P93000; -.
DR PRIDE; P93000; -.
DR ProteomicsDB; 248500; -.
DR EnsemblPlants; AT3G05930.1; AT3G05930.1; AT3G05930.
DR GeneID; 819762; -.
DR Gramene; AT3G05930.1; AT3G05930.1; AT3G05930.
DR KEGG; ath:AT3G05930; -.
DR Araport; AT3G05930; -.
DR TAIR; locus:2074489; AT3G05930.
DR eggNOG; ENOG502QQ4A; Eukaryota.
DR HOGENOM; CLU_015790_0_3_1; -.
DR InParanoid; P93000; -.
DR OMA; HMAIADT; -.
DR OrthoDB; 1164277at2759; -.
DR PhylomeDB; P93000; -.
DR PRO; PR:P93000; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; P93000; baseline and differential.
DR Genevisible; P93000; AT.
DR GO; GO:0048046; C:apoplast; IEA:UniProtKB-SubCell.
DR GO; GO:0009506; C:plasmodesma; IBA:GO_Central.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0010497; P:plasmodesmata-mediated intercellular transport; IBA:GO_Central.
DR GO; GO:2000280; P:regulation of root development; IBA:GO_Central.
DR Gene3D; 2.60.120.10; -; 1.
DR InterPro; IPR006045; Cupin_1.
DR InterPro; IPR001929; Germin.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR Pfam; PF00190; Cupin_1; 1.
DR PRINTS; PR00325; GERMIN.
DR SMART; SM00835; Cupin_1; 1.
DR SUPFAM; SSF51182; SSF51182; 1.
PE 2: Evidence at transcript level;
KW Apoplast; Disulfide bond; Glycoprotein; Manganese; Metal-binding;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..219
FT /note="Germin-like protein subfamily 2 member 3"
FT /id="PRO_0000010823"
FT DOMAIN 60..209
FT /note="Cupin type-1"
FT /evidence="ECO:0000255"
FT BINDING 109
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT BINDING 111
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT BINDING 116
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT BINDING 155
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000250"
FT CARBOHYD 70
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 31..46
FT /evidence="ECO:0000250"
SQ SEQUENCE 219 AA; 23033 MW; D344858985178CFD CRC64;
MATSMIPIFV TFMLVAAHMA LADTNMLQDF CVADLSNGLK VNGYPCKDPA KVTPEDFYFI
GLATAAATAN SSMGSAVTGA NVEKVPGLNT LGVSISRIDY APGGLNPPHL HPRASEAIFV
LEGRLFVGFL TTTGKLISKH VNKGDVFVFP KALLHFQQNP NKAPASVLAA FDSQLPGTQV
VGPSLFGSNP PIPDDLLAKA FGAAAPEIQK IKGKFPPKK
