ID   GL8D1_BOVIN             Reviewed;         371 AA.
AC   Q5E9E7;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Glycosyltransferase 8 domain-containing protein 1;
DE            EC=2.4.1.-;
GN   Name=GLT8D1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Uterus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. {ECO:0000305}.
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DR   EMBL; BT020973; AAX08990.1; -; mRNA.
DR   EMBL; BC113277; AAI13278.1; -; mRNA.
DR   RefSeq; NP_001015579.1; NM_001015579.1.
DR   AlphaFoldDB; Q5E9E7; -.
DR   SMR; Q5E9E7; -.
DR   STRING; 9913.ENSBTAP00000019340; -.
DR   CAZy; GT8; Glycosyltransferase Family 8.
DR   PaxDb; Q5E9E7; -.
DR   PRIDE; Q5E9E7; -.
DR   Ensembl; ENSBTAT00000019340; ENSBTAP00000019340; ENSBTAG00000014550.
DR   GeneID; 512192; -.
DR   KEGG; bta:512192; -.
DR   CTD; 55830; -.
DR   VEuPathDB; HostDB:ENSBTAG00000014550; -.
DR   VGNC; VGNC:29423; GLT8D1.
DR   eggNOG; ENOG502QTN8; Eukaryota.
DR   GeneTree; ENSGT00940000159273; -.
DR   HOGENOM; CLU_010770_0_0_1; -.
DR   InParanoid; Q5E9E7; -.
DR   OMA; ARFYLPM; -.
DR   OrthoDB; 1520602at2759; -.
DR   TreeFam; TF332433; -.
DR   Proteomes; UP000009136; Chromosome 22.
DR   Bgee; ENSBTAG00000014550; Expressed in spermatocyte and 104 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR002495; Glyco_trans_8.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF01501; Glyco_transf_8; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Glycosyltransferase; Membrane; Reference proteome;
KW   Signal-anchor; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..371
FT                   /note="Glycosyltransferase 8 domain-containing protein 1"
FT                   /id="PRO_0000288527"
FT   TOPO_DOM        1..7
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        8..28
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..371
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        103
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        257
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   371 AA;  41958 MW;  858C650C2757C768 CRC64;
     MSFRKVNIVI LVLAVALFLL VLHHNFLGLS SLLRNEVSDS GIVGLQPVDF IPNAPQRVVD
     GREEEIPVVI AASEDRLGGA IAAINSIQHN TRSNVIFYIV TLNGTADHLR SWLSSSNLKR
     IRYKIVNFDT KLLEGKVKED PDQGESIKPL TFARFYLPIL VPRAKKAIYM DDDVIVQGDI
     LALYNTPLKP GHAAAFSEDC DSTSAKVVIR GAGNQYNYIG YLDYKKERIR ELSMKASTCS
     FNPGVFVANL TEWRRQNITN QLEKWMKLNV EEGLYSRTLA GSITTPPLLI VFYQQHSTID
     PMWNVRHLGS SAGKRYSPQF VKAAKLLHWN GHFKPWGRTA SYTDVWEKWY IPDPTGKFSL
     IRRHVEISNT K