ID   GL8D1_DANRE             Reviewed;         365 AA.
AC   Q5U3H3;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Glycosyltransferase 8 domain-containing protein 1;
DE            EC=2.4.1.-;
GN   Name=glt8d1; ORFNames=zgc:103525;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. {ECO:0000305}.
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DR   EMBL; BC085543; AAH85543.1; -; mRNA.
DR   RefSeq; NP_001007339.1; NM_001007338.1.
DR   AlphaFoldDB; Q5U3H3; -.
DR   SMR; Q5U3H3; -.
DR   STRING; 7955.ENSDARP00000058734; -.
DR   CAZy; GT8; Glycosyltransferase Family 8.
DR   PaxDb; Q5U3H3; -.
DR   GeneID; 492466; -.
DR   KEGG; dre:492466; -.
DR   CTD; 55830; -.
DR   ZFIN; ZDB-GENE-041114-23; glt8d1.
DR   eggNOG; ENOG502QTN8; Eukaryota.
DR   InParanoid; Q5U3H3; -.
DR   OrthoDB; 1520602at2759; -.
DR   PhylomeDB; Q5U3H3; -.
DR   PRO; PR:Q5U3H3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR002495; Glyco_trans_8.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF01501; Glyco_transf_8; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Glycosyltransferase; Membrane; Reference proteome;
KW   Signal-anchor; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..365
FT                   /note="Glycosyltransferase 8 domain-containing protein 1"
FT                   /id="PRO_0000288531"
FT   TOPO_DOM        1..4
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        5..22
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        23..365
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        102
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        181
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        245
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        253
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   365 AA;  41353 MW;  0830DA1692F23E13 CRC64;
     MTVRRVNVVI LVLLVVAFLI VLHRNLLNLN DFLNQETSDT VPGMILPFET DFLLGRKAMR
     SGEEIPVLIT APEERLGAAV TAMNSIYRNS KANVVFNIVT LNESVVHLST WLSKTDLKHK
     IIVFDPSILL GKIPTDAQKM ETVRPLTFAR FYMPAFLPDA EKAIYLDDDV IVQGDIRELF
     NTSLKSGHVA AFSEDCDSAS SKGIVRGAGN QNSYIGYLDF KKEAIKKLGM RANTCSFNPG
     VFVANLTEWK QQNVTSQLEF WMERNAKEDL YSKTLADCMT TPPMLIVFYK HHSNIDPMWN
     VRHLGATGAG NRYSAQFVKA AKLLHWNGHY KPWGRTSSFS DIWDKWYIPD PTGKFHPIRK
     HVEEK